Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LATS1 | O95835 | 2/20 | 0.45 |
| ▸ | SLC22A12 | Q96S37 | 2/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | DGAT2 | Q96PD7 | 1/20 | 0.33 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.33 |
| ▸ | MAPK9 | P45984 | 1/20 | 0.33 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.33 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.33 |
| ▸ | MMP8 | P22894 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21350533 | 0.90 | LATS1 (0.43) | LATS1SLC22A12MAPK1SMN1; SMN2PTGS1 | |
| SCHEMBL21350308 | 0.87 | LATS1 (0.41) | LATS1SLC22A12DGAT2KDM4C | |
| SCHEMBL21350752 | 0.87 | SLC22A12 (0.55) | LATS1SLC22A12 | |
| SCHEMBL28408726 | 0.87 | SLC22A12 (0.46) | LATS1SLC22A12PTGS1MAPK8MAPK9 | |
| SCHEMBL21350307 | 0.80 | ELANE (0.42) | SLC22A12SMN1; SMN2TP53DGAT2MAPK8 | |
| SCHEMBL21350897 | 0.79 | SLC22A12 (0.57) | SLC22A12 | |
| SCHEMBL21333987 | 0.75 | SLC22A12 (0.46) | LATS1SLC22A12MAPK8MAPK9MAPK10 | |
| SCHEMBL21350531 | 0.74 | KDM4E (0.38) | SLC22A12SMN1; SMN2MAPTHSD17B10ALDH1A1 | |
| SCHEMBL21350537 | 0.74 | CYP4F2 (0.52) | SLC22A12SMN1; SMN2DGAT2MAPTALDH1A1 | |
| SCHEMBL21333904 | 0.74 | SLC22A12 (0.39) | SLC22A12MAPK8MAPK9MAPK10KDM4C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019169890-A1 | 3-(NAPHTHALENE-1-METHYL SUBSTITUTED)PYRIDINE DERIVATIVE, SYNTHETIC METHOD THEREFOR AND USE THEREOF | 南方医科大学 | 2019-09-12 | — | — | WO | disclosed |