Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LATS1 | O95835 | 1/20 | 0.43 |
| ▸ | SLC22A12 | Q96S37 | 2/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | NAMPT | P43490 | 1/20 | 0.36 |
| ▸ | DGAT2 | Q96PD7 | 1/20 | 0.34 |
| ▸ | BUB1 | O43683 | 2/20 | 0.34 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | GPBAR1 | Q8TDU6 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.32 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.32 |
| ▸ | MAPK9 | P45984 | 1/20 | 0.32 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.32 |
| ▸ | TP53 | P04637 | 1/20 | 0.32 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.32 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21350630 | 0.90 | LATS1 (0.45) | LATS1SLC22A12SMN1; SMN2MAPK1DGAT2 | |
| SCHEMBL21333987 | 0.86 | SLC22A12 (0.46) | LATS1SLC22A12MAPK8MAPK9MAPK10 | |
| SCHEMBL21350308 | 0.85 | LATS1 (0.41) | LATS1SLC22A12DGAT2 | |
| SCHEMBL21350752 | 0.85 | SLC22A12 (0.55) | LATS1SLC22A12 | |
| SCHEMBL21350903 | 0.81 | PPARA (0.39) | LATS1SLC22A12SMN1; SMN2MAPK1NAMPT | |
| SCHEMBL21350532 | 0.81 | ELANE (0.41) | SLC22A12NAMPTDGAT2BUB1FFAR1 | |
| SCHEMBL21350293 | 0.80 | SLC22A12 (0.56) | SLC22A12 | |
| SCHEMBL28408726 | 0.77 | SLC22A12 (0.46) | LATS1SLC22A12NAMPTMAPK8MAPK9 | |
| SCHEMBL21350306 | 0.76 | KDM4E (0.37) | SLC22A12SMN1; SMN2NAMPTFFAR1MAPT | |
| SCHEMBL21350909 | 0.75 | CYP4F2 (0.50) | SLC22A12SMN1; SMN2NAMPTDGAT2FFAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019169890-A1 | 3-(NAPHTHALENE-1-METHYL SUBSTITUTED)PYRIDINE DERIVATIVE, SYNTHETIC METHOD THEREFOR AND USE THEREOF | 南方医科大学 | 2019-09-12 | — | — | WO | disclosed |