Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRM1 | P35372 | 20/20 | 0.71 |
| ▸ | SIGMAR1 | Q99720 | 19/20 | 0.71 |
| ▸ | KCNH2 | Q12809 | 8/20 | 0.68 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18425512 | 0.93 | OPRM1 (0.81) | OPRM1SIGMAR1KCNH2 | |
| SCHEMBL20599083 | 0.87 | OPRM1 (0.88) | OPRM1SIGMAR1KCNH2 | |
| SCHEMBL18458752 | 0.85 | OPRM1 (0.85) | OPRM1SIGMAR1KCNH2 | |
| SCHEMBL18426684 | 0.83 | OPRM1 (1.00) | OPRM1SIGMAR1KCNH2 | |
| SCHEMBL20598998 | 0.81 | SIGMAR1 (1.00) | OPRM1SIGMAR1KCNH2 | |
| SCHEMBL18423525 | 0.80 | OPRM1 (0.82) | OPRM1SIGMAR1KCNH2 | |
| SCHEMBL18458961 | 0.79 | OPRM1 (0.80) | OPRM1SIGMAR1KCNH2 | |
| SCHEMBL20599321 | 0.79 | OPRM1 (0.74) | OPRM1SIGMAR1KCNH2 | |
| SCHEMBL18426257 | 0.78 | OPRM1 (0.81) | OPRM1SIGMAR1KCNH2 | |
| SCHEMBL20598997 | 0.77 | OPRM1 (0.79) | OPRM1SIGMAR1KCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3328853-B1 | SUBSTITUTED AMIDE DERIVATIVES HAVING MULTIMODAL ACTIVITY AGAINST PAIN | ESTEVE PHARMACEUTICALS SA (ES) | 2019-09-11 | — | — | EP | disclosed |