Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRM1 | P35372 | 20/20 | 0.53 |
| ▸ | SIGMAR1 | Q99720 | 19/20 | 0.53 |
| ▸ | KCNH2 | Q12809 | 7/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19631785 | 0.78 | OPRM1 (0.44) | OPRM1SIGMAR1KCNH2 | |
| SCHEMBL18426780 | 0.77 | SIGMAR1 (0.87) | OPRM1SIGMAR1KCNH2 | |
| SCHEMBL18458749 | 0.77 | OPRM1 (0.84) | OPRM1SIGMAR1KCNH2 | |
| SCHEMBL21337545 | 0.74 | SIGMAR1 (0.81) | OPRM1SIGMAR1KCNH2 | |
| SCHEMBL18426573 | 0.74 | OPRM1 (0.64) | OPRM1SIGMAR1KCNH2 | |
| SCHEMBL18458333 | 0.74 | SIGMAR1 (0.82) | OPRM1SIGMAR1KCNH2 | |
| SCHEMBL20599205 | 0.73 | OPRM1 (0.75) | OPRM1SIGMAR1KCNH2 | |
| SCHEMBL18425865 | 0.73 | SIGMAR1 (0.68) | OPRM1SIGMAR1KCNH2 | |
| SCHEMBL19631711 | 0.73 | OPRM1 (0.46) | OPRM1SIGMAR1 | |
| SCHEMBL21337558 | 0.73 | SIGMAR1 (0.73) | OPRM1SIGMAR1KCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3328853-B1 | SUBSTITUTED AMIDE DERIVATIVES HAVING MULTIMODAL ACTIVITY AGAINST PAIN | ESTEVE PHARMACEUTICALS SA (ES) | 2019-09-11 | — | — | EP | disclosed |