Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 2/20 | 0.40 |
| ▸ | HTT | P42858 | 2/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14805610 | 0.85 | TDP1 (0.41) | TDP1LMNAPOLBNPSR1L3MBTL1 | |
| SCHEMBL14432031 | 0.81 | KMT2A (0.59) | TDP1LMNAPOLBNPSR1ALDH1A1 | |
| SCHEMBL8577301 | 0.79 | TDP1 (0.49) | TDP1LMNAMAPTPOLBALDH1A1 | |
| SCHEMBL2724979 | 0.78 | NPC1 (0.55) | MAPTPOLBALDH1A1 | |
| SCHEMBL13884318 | 0.77 | ALDH1A1 (0.42) | LMNAMAPTPOLBNPSR1L3MBTL1 | |
| SCHEMBL22775250 | 0.77 | TDP1 (0.47) | TDP1LMNAMAPTPOLBL3MBTL1 | |
| SCHEMBL22548989 | 0.76 | NPSR1 (0.51) | TDP1LMNAMAPTPOLBNPSR1 | |
| SCHEMBL12403825 | 0.76 | MEN1 (0.53) | NPSR1 | |
| SCHEMBL29134654 | 0.76 | MEN1 (0.56) | TDP1LMNAMAPTPOLBNPSR1 | |
| SCHEMBL10294742 | 0.75 | HDAC8 (0.56) | LMNAMAPTNPSR1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2726459-B1 | SULFAMOYLBENZAMIDE DERIVATIVES AS ANTIVIRAL AGENTS AGAINST HBV INFECTION | BARUCH S BLUMBERG INST (US) | 2019-09-11 | — | — | EP | disclosed |