Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12852717 | 0.82 | TDP1 (0.43) | TDP1ALDH1A1MEN1KMT2ATSHR | |
| SCHEMBL14278752 | 0.82 | TDP1 (0.43) | TDP1ALDH1A1MEN1KMT2ATSHR | |
| SCHEMBL22775250 | 0.82 | TDP1 (0.47) | TDP1ALDH1A1MEN1KMT2ASMN1; SMN2 | |
| SCHEMBL29134654 | 0.80 | MEN1 (0.56) | TDP1ALDH1A1MEN1KMT2ATSHR | |
| SCHEMBL167439 | 0.79 | FURIN (0.43) | TDP1TSHRLMNAMAPTHTT | |
| SCHEMBL30478066 | 0.79 | ALDH1A1 (0.66) | TDP1ALDH1A1MEN1KMT2ASMN1; SMN2 | |
| SCHEMBL7768635 | 0.79 | ALDH1A1 (0.66) | TDP1ALDH1A1MEN1KMT2ASMN1; SMN2 | |
| SCHEMBL24548087 | 0.79 | TDP1 (0.62) | TDP1ALDH1A1MEN1KMT2ATSHR | |
| SCHEMBL21337593 | 0.79 | TDP1 (0.45) | TDP1ALDH1A1TSHRLMNAMAPT | |
| SCHEMBL19142437 | 0.79 | TDP1 (0.49) | TDP1ALDH1A1MEN1KMT2ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2726459-B1 | SULFAMOYLBENZAMIDE DERIVATIVES AS ANTIVIRAL AGENTS AGAINST HBV INFECTION | BARUCH S BLUMBERG INST (US) | 2019-09-11 | — | — | EP | disclosed |
| EP-3357898-A1 | METHOD FOR PRODUCING ORGANIC COMPOUND | Fujifilm Finechemicals Co., Ltd. (JP) | 2018-08-08 | — | — | EP | disclosed |
| US-5736298-A | COMPRISES A PARTICULATE POLYMER OF A CARBOXY-GROUP-CONTAINING-DIENE HAVING A CROSSLINKED STRUCTURE | JAPAN SYNTHETIC RUBBER CO., LTD. (JP) | 1998-04-07 | — | — | US | disclosed |