Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIK3CD | O00329 | 18/20 | 0.47 |
| ▸ | RET | P07949 | 2/20 | 0.45 |
| ▸ | PIK3CB | P42338 | 6/20 | 0.42 |
| ▸ | PIK3CG | P48736 | 3/20 | 0.42 |
| ▸ | PIK3CA | P42336 | 2/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16783387 | 0.91 | RET (0.44) | PIK3CDRETPIK3CBPIK3CGPIK3CA | |
| SCHEMBL16783540 | 0.88 | PIK3CD (0.46) | PIK3CDRETPIK3CBPIK3CGPIK3CA | |
| SCHEMBL21337793 | 0.83 | PIK3CD (0.45) | PIK3CDPIK3CBPIK3CG | |
| SCHEMBL16783810 | 0.83 | PIK3CD (0.57) | PIK3CDPIK3CBPIK3CGPIK3CA | |
| Hydrochloric Acid SCHEMBL16783839 | 0.82 | PIK3CD (0.56) | PIK3CDPIK3CBPIK3CGPIK3CA | |
| SCHEMBL21337670 | 0.81 | PIK3CD (0.40) | PIK3CDPIK3CBPIK3CGPIK3CA | |
| SCHEMBL21337664 | 0.81 | PIK3CD (0.40) | PIK3CDPIK3CBPIK3CGPIK3CA | |
| SCHEMBL21337782 | 0.81 | PIK3CD (0.40) | PIK3CDPIK3CBPIK3CGPIK3CA | |
| SCHEMBL21337767 | 0.80 | PIK3CD (0.47) | PIK3CDRETPIK3CBPIK3CG | |
| SCHEMBL21337672 | 0.80 | PIK3CD (0.47) | PIK3CDRETPIK3CBPIK3CGPIK3CA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3083617-B1 | ISOCHROMENE DERIVATIVES AS PHOSPHOINOSITIDE 3-KINASES INHIBITORS | CHIESI FARM SPA (IT) | 2019-09-11 | — | — | EP | disclosed |