Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2C | P28335 | 4/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | FYN | P06241 | 1/20 | 0.40 |
| ▸ | HTR6 | P50406 | 1/20 | 0.40 |
| ▸ | PLAT | P00750 | 3/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.36 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.36 |
| ▸ | HTR5A | P47898 | 2/20 | 0.35 |
| ▸ | JAK2 | O60674 | 1/20 | 0.35 |
| ▸ | JAK3 | P52333 | 1/20 | 0.35 |
| ▸ | PTK2 | Q05397 | 1/20 | 0.35 |
| ▸ | JUND | P17535 | 1/20 | 0.35 |
| ▸ | FOSB | P53539 | 1/20 | 0.35 |
| ▸ | CCNT1 | O60563 | 2/20 | 0.35 |
| ▸ | CDK9 | P50750 | 2/20 | 0.35 |
| ▸ | CDK1 | P06493 | 1/20 | 0.35 |
| ▸ | CDK2 | P24941 | 1/20 | 0.35 |
| ▸ | CASP3 | P42574 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6716568 | 0.77 | HTR2C (0.47) | HTR2CMEN1KMT2AFYNHTR6 | |
| SCHEMBL21339719 | 0.76 | NOS2 (0.49) | HTR2CMEN1KMT2ASLC6A2SLC6A4 | |
| SCHEMBL6748973 | 0.65 | HTR2C (0.63) | HTR2CMEN1KMT2AHTR6PLAT | |
| SCHEMBL5584891 | 0.65 | HTR2C (0.59) | HTR2CMEN1KMT2AHTR6TDP1 | |
| SCHEMBL2707057 | 0.65 | HTR2C (0.63) | HTR2CMEN1KMT2AHTR6SLC6A2 | |
| SCHEMBL5584716 | 0.65 | HTR2C (0.69) | HTR2CMEN1KMT2AHTR6TDP1 | |
| SCHEMBL239790 | 0.65 | HTR2C (0.64) | HTR2CMEN1KMT2AHTR6TDP1 | |
| Hydrochloric Acid SCHEMBL23411498 | 0.64 | HTR2C (0.94) | HTR2CFYN | |
| SCHEMBL22324792 | 0.64 | HTR2C (0.58) | HTR2CMEN1KMT2AHTR6TDP1 | |
| SCHEMBL1529068 | 0.64 | HTR2C (0.58) | HTR2CMEN1KMT2AHTR6SLC6A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019170543-A1 | IDENTIFICATION AND USE OF ERK5 INHIBITORS | BAYER AKTIENGESELLSCHAFT (DE) | 2019-09-12 | — | — | WO | disclosed |