SCHEMBL3954232

SCHEMBL3954232

CC(C)CCC[C@@H](C)[C@H]1CC[C@H]2[C@@H]3CC=C4C[C@@H](OC(=O)CCCCC(=O)O)CC[C@]4(C)[C@H]3CC[C@]12C

nearest known ligand 0.85

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
POLA1 P09884 1/20 0.77
CYP46A1 Q9Y6A2 2/20 0.70
USP2 O75604 1/20 0.66
LMNA P02545 1/20 0.66
ABCB1 P08183 1/20 0.66
OSBP P22059 1/20 0.66
RORC P51449 1/20 0.66
OSBP2 Q969R2 1/20 0.66
EPHA2 P29317 1/20 0.64
NR1H3 Q13133 1/20 0.64

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27319635 1.00 POLA1 (0.77) POLA1CYP46A1USP2LMNAABCB1
SCHEMBL25351944 1.00 POLA1 (0.77) POLA1CYP46A1USP2LMNAABCB1
SCHEMBL2134010 1.00 POLA1 (0.77) POLA1CYP46A1USP2LMNAABCB1
SCHEMBL3954234 1.00 POLA1 (0.77) POLA1CYP46A1USP2LMNAABCB1
SCHEMBL27320877 0.99 POLA1 (0.75) POLA1CYP46A1USP2LMNAABCB1
SCHEMBL11426770 0.99 POLA1 (0.75) POLA1CYP46A1USP2LMNAABCB1
SCHEMBL27883156 0.99 POLA1 (0.75) POLA1CYP46A1USP2LMNAABCB1
SCHEMBL27320857 0.99 POLA1 (0.75) POLA1CYP46A1USP2LMNAABCB1
SCHEMBL8608992 0.99 POLA1 (0.75) POLA1CYP46A1USP2LMNAABCB1
SCHEMBL28088866 0.99 POLA1 (0.75) POLA1CYP46A1USP2LMNAABCB1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 21 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20260109732-A1 LIPID AMINES MODERNATX INC (US) 2026-04-23 US disclosed
US-20250235531-A1 MUCOSAL ADMINISTRATION METHODS AND FORMULATIONS MODERNATX, INC. (US) 2025-07-24 US disclosed
EP-4475882-A1 MUCOSAL ADMINISTRATION METHODS AND FORMULATIONS ModernaTX, Inc. (US) 2024-12-18 EP disclosed
EP-4423107-A1 LIPID AMINES ModernaTX, Inc. (US) 2024-09-04 EP disclosed
EP-4393484-A1 COMPOSITION FOR ORGAN-SPECIFIC DELIVERY OF NUCLEIC ACID Themedium Therapeutics Co., Ltd. (CN) 2024-07-03 EP disclosed
WO-2023154818-A1 MUCOSAL ADMINISTRATION METHODS AND FORMULATIONS MODERNATX, INC. (US) 2023-08-17 WO disclosed
WO-2023154818-A1 MUCOSAL ADMINISTRATION METHODS AND FORMULATIONS MODERNATX, INC. (US) 2023-08-17 WO disclosed
WO-2023076598-A1 LIPID AMINES MODERNATX, INC. (US) 2023-05-04 WO disclosed
WO-2023076598-A1 LIPID AMINES MODERNATX, INC. (US) 2023-05-04 WO disclosed
CN-108700678-B Antireflection film and method for producing antireflection film 富士胶片株式会社 2020-04-21 CN disclosed
US-8349306-B2 Hydrophilic comonomers of alkylene glycol, vinyl alcohols, vinylpyrrolidone, and/or acrylamide; hydrophobic comonoomer of lactic acid, glycolic acid, 6-hydroxycaproic acid, and/or dioxan-2-one substituted with tocopherol or cholesterol; stable micelles for delivery of anticarcinogenic agents SAMYANG BIOPHARMACEUTICALS CORPORATION (KR) 2013-01-08 US disclosed
EP-1670838-A4 AMPHIPHILIC BLOCK COPOLYMER AND POLYMERIC COMPOSITION COMPRISING THE SAME FOR DRUG DELIVERY SAMYANG CORP (KR) 2009-07-08 EP disclosed
CN-100471886-C Amphiphilic block copolymer and polymeric composition comprising the same for drug delivery SAMYANG CORP (KR) 2009-03-25 CN disclosed
US-20080152616-A1 Amphiphilic block copolymer and polymeric compostition comprising the same for drug delivery SAMYANG HOLDINGS CORPORATION (KR) 2008-06-26 US disclosed
US-7311901-B2 Amphiphilic block copolymer and polymeric composition comprising the same for drug delivery SAMYANG CORPORATION (KR) 2007-12-25 US disclosed
EP-1670838-A1 AMPHIPHILIC BLOCK COPOLYMER AND POLYMERIC COMPOSITION COMPRISING THE SAME FOR DRUG DELIVERY Samyang Corporation (KR) 2006-06-21 EP disclosed
CN-1780865-A Amphiphilic block copolymer and polymeric composition comprising the same for drug delivery SAMYANG CORP (KR) 2006-05-31 CN disclosed
US-20050201972-A1 Amphiphilic block copolymer and polymeric composition comprising the same for drug delivery SAMYANG CORPORATION 2005-09-15 US disclosed
WO-2005035606-A1 AMPHIPHILIC BLOCK COPOLYMER AND POLYMERIC COMPOSITION COMPRISING THE SAME FOR DRUG DELIVERY SAMYANG CORPORATION (KR) 2005-04-21 WO disclosed
US-4040784-A Method for checking the accuracy of a test, using a serum-soluble cholesterol compound MONOBIND, INC., A CORP. OF CA. 1977-08-09 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20080152616-A1 Amphiphilic block copolymer and polymeric compostition comprising the same for drug delivery CETP, ABCB4, TPRKB POLA1 2142/4885CYP46A1 22/4885USP2 1543/4885
US-20250235531-A1 MUCOSAL ADMINISTRATION METHODS AND FORMULATIONS MUC1, RNMT, FABP2 POLA1 1481/4885CYP46A1 1475/4885USP2 1671/4885
US-20050201972-A1 Amphiphilic block copolymer and polymeric composition comprising the same for drug delivery TTPA, CETP, CHKB POLA1 2927/4885CYP46A1 110/4885USP2 1332/4885
US-20260109732-A1 LIPID AMINES LDLR, NPC1, PHOSPHO1 POLA1 2294/4885CYP46A1 156/4885USP2 3959/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.