SCHEMBL21341978

SCHEMBL21341978

COc1ccc(C2CNC(=O)C[C@@H]2NC(=O)Nc2ccc(Br)cc2)cc1

nearest known ligand 0.85

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
FPR1 P21462 19/20 0.85
FPR2 P25090 13/20 0.68

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21332044 1.00 FPR1 (0.85) FPR1FPR2
SCHEMBL19972221 0.92 FPR1 (1.00) FPR1FPR2
SCHEMBL19972218 0.92 FPR1 (1.00) FPR1FPR2
SCHEMBL21341981 0.90 FPR1 (0.85) FPR1FPR2
SCHEMBL21341973 0.90 FPR1 (0.85) FPR1FPR2
SCHEMBL21332003 0.84 FPR1 (0.71) FPR1FPR2
SCHEMBL21331924 0.84 FPR1 (0.73) FPR1FPR2
SCHEMBL21342398 0.82 FPR1 (0.84) FPR1FPR2
SCHEMBL21332211 0.82 FPR1 (0.84) FPR1FPR2
SCHEMBL21342311 0.82 FPR1 (0.84) FPR1FPR2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2019170904-A1 PIPERIDINES OR PIPERIDONES SUBSTITUTED WITH UREA AND PHENYL Grünenthal GmbH (DE) 2019-09-12 WO disclosed