SCHEMBL21341981

SCHEMBL21341981

COc1ccc(C2CNC(=O)C[C@H]2NC(=O)Nc2ccc(Cl)cc2)cc1

nearest known ligand 0.85

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
FPR1 P21462 19/20 0.85
FPR2 P25090 14/20 0.85

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21341973 1.00 FPR1 (0.85) FPR1FPR2
SCHEMBL19972300 0.92 FPR1 (1.00) FPR1FPR2
SCHEMBL19988412 0.92 FPR1 (1.00) FPR1FPR2
SCHEMBL19972297 0.92 FPR1 (1.00) FPR1FPR2
SCHEMBL21341978 0.90 FPR1 (0.85) FPR1FPR2
SCHEMBL21332044 0.90 FPR1 (0.85) FPR1FPR2
SCHEMBL21332080 0.84 FPR1 (0.86) FPR1FPR2
SCHEMBL21342023 0.84 FPR1 (0.86) FPR1FPR2
SCHEMBL18106480 0.83 FPR2 (1.00) FPR1FPR2
SCHEMBL16785417 0.83 FPR2 (1.00) FPR1FPR2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2019170904-A1 PIPERIDINES OR PIPERIDONES SUBSTITUTED WITH UREA AND PHENYL Grünenthal GmbH (DE) 2019-09-12 WO disclosed