Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.52 |
| ▸ | KIF11 | P52732 | 6/20 | 0.51 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.48 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.46 |
| ▸ | USP30 | Q70CQ3 | 2/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
| ▸ | CLK2 | P49760 | 1/20 | 0.44 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.44 |
| ▸ | CDK5 | Q00535 | 1/20 | 0.44 |
| ▸ | CDK5R1 | Q15078 | 1/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.44 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.44 |
| ▸ | SLC22A8 | Q8TCC7 | 1/20 | 0.44 |
| ▸ | SLC22A12 | Q96S37 | 1/20 | 0.44 |
| ▸ | SLC22A11 | Q9NSA0 | 1/20 | 0.44 |
| ▸ | TRPV4 | Q9HBA0 | 1/20 | 0.44 |
| ▸ | PEPD | P12955 | 1/20 | 0.44 |
| ▸ | KCNQ3 | O43525 | 1/20 | 0.43 |
| ▸ | KCNQ2 | O43526 | 1/20 | 0.43 |
| ▸ | KCNE1 | P15382 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2225852 | 0.84 | TRPV1 (0.49) | TRPV1EPHX2USP30CLK2DYRK1A | |
| SCHEMBL29585632 | 0.84 | TRPV1 (0.49) | TRPV1EPHX2USP30CLK2DYRK1A | |
| SCHEMBL1204250 | 0.83 | KIF11 (0.51) | ALDH1A1KIF11TRPV1EPHX2USP30 | |
| SCHEMBL9906890 | 0.83 | KDM4E (0.55) | TRPV1EPHX2USP30SMN1; SMN2CLK2 | |
| SCHEMBL24974096 | 0.80 | MAPT (0.50) | ALDH1A1TRPV1EPHX2USP30CLK2 | |
| SCHEMBL3573330 | 0.80 | SMN1; SMN2 (0.47) | ALDH1A1TRPV1EPHX2USP30SMN1; SMN2 | |
| SCHEMBL21503709 | 0.79 | MLYCD (0.53) | ALDH1A1TRPV1EPHX2USP30SMN1; SMN2 | |
| SCHEMBL20097426 | 0.79 | ATM (0.53) | TRPV1EPHX2USP30SMN1; SMN2NPC1 | |
| SCHEMBL21580308 | 0.79 | TRPV1 (0.46) | TRPV1EPHX2USP30CLK2DYRK1A | |
| SCHEMBL5778192 | 0.76 | NAMPT (0.49) | TRPV1EPHX2USP30CYP2C9SLC22A6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023176554-A1 | COGNITIVE-FUNCTION-IMPROVING AGENT | 国立大学法人東北大学 | 2023-09-21 | — | — | WO | claimed |
| WO-2023176554-A1 | COGNITIVE-FUNCTION-IMPROVING AGENT | 国立大学法人東北大学 | 2023-09-21 | — | — | WO | disclosed |
| EP-3634955-B1 | PIPERIDINONE FORMYL PEPTIDE 2 RECEPTOR AGONISTS | BRISTOL MYERS SQUIBB CO (US) | 2021-03-31 | — | — | EP | disclosed |
| WO-2019170904-A1 | PIPERIDINES OR PIPERIDONES SUBSTITUTED WITH UREA AND PHENYL | Grünenthal GmbH (DE) | 2019-09-12 | — | — | WO | disclosed |