SCHEMBL21341999

SCHEMBL21341999

COc1ccc(C2CN(c3ccc(F)cc3)C(=O)C[C@H]2NC(=O)Nc2ccc(Cl)cc2)cc1

nearest known ligand 0.64

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
FPR1 P21462 14/20 0.64
FPR2 P25090 14/20 0.64

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21332006 1.00 FPR1 (0.64) FPR1FPR2
SCHEMBL21332077 0.95 FPR1 (0.69) FPR1FPR2
SCHEMBL21342339 0.95 FPR1 (0.69) FPR1FPR2
SCHEMBL23062397 0.87 FPR1 (0.49) FPR1FPR2
SCHEMBL23062121 0.87 FPR1 (0.49) FPR1FPR2
SCHEMBL23062073 0.87 FPR1 (0.51) FPR1FPR2
SCHEMBL23062119 0.87 FPR1 (0.49) FPR1FPR2
SCHEMBL23062075 0.87 FPR1 (0.51) FPR1FPR2
SCHEMBL23062367 0.87 FPR1 (0.51) FPR1FPR2
SCHEMBL21335101 0.85 FPR1 (0.64) FPR1FPR2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2019170904-A1 PIPERIDINES OR PIPERIDONES SUBSTITUTED WITH UREA AND PHENYL Grünenthal GmbH (DE) 2019-09-12 WO disclosed