Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FPR1 | P21462 | 15/20 | 0.51 |
| ▸ | FPR2 | P25090 | 10/20 | 0.51 |
| ▸ | MAPT | P10636 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23062075 | 1.00 | FPR1 (0.51) | FPR1FPR2MAPTALDH1A1LMNA | |
| SCHEMBL23062367 | 1.00 | FPR1 (0.51) | FPR1FPR2MAPTALDH1A1LMNA | |
| SCHEMBL23062302 | 0.91 | FPR2 (0.45) | FPR1FPR2MAPTALDH1A1LMNA | |
| SCHEMBL23062160 | 0.91 | FPR2 (0.45) | FPR1FPR2MAPTALDH1A1LMNA | |
| SCHEMBL21341999 | 0.87 | FPR1 (0.64) | FPR1FPR2 | |
| SCHEMBL21332006 | 0.87 | FPR1 (0.64) | FPR1FPR2 | |
| SCHEMBL23062228 | 0.84 | FPR1 (0.56) | FPR1FPR2MAPTALDH1A1LMNA | |
| SCHEMBL23062397 | 0.84 | FPR1 (0.49) | FPR1FPR2MAPT | |
| SCHEMBL23062121 | 0.84 | FPR1 (0.49) | FPR1FPR2MAPT | |
| SCHEMBL23062119 | 0.84 | FPR1 (0.49) | FPR1FPR2MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3789378-A1 | PIPERIDINES OR PIPERIDONES SUBSTITUTED WITH UREA AND HETEROARYL | Grünenthal GmbH (DE) | 2021-03-10 | — | — | EP | claimed |
| EP-3789378-A1 | PIPERIDINES OR PIPERIDONES SUBSTITUTED WITH UREA AND HETEROARYL | Grünenthal GmbH (DE) | 2021-03-10 | — | — | EP | disclosed |