Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.51 |
| ▸ | MAPT | P10636 | 4/20 | 0.50 |
| ▸ | KDM1A | O60341 | 1/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.50 |
| ▸ | TP53 | P04637 | 1/20 | 0.48 |
| ▸ | PDE4B | Q07343 | 2/20 | 0.47 |
| ▸ | GFER | P55789 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.47 |
| ▸ | ATM | Q13315 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21342000 | 0.88 | KDM1A (0.44) | LMNAMAPTKDM1AKDM4ETP53 | |
| SCHEMBL21342456 | 0.87 | FPR1 (0.53) | LMNAKDM1APDE4BALDH1A1 | |
| SCHEMBL21342416 | 0.83 | KDM1A (0.43) | LMNAMAPTKDM1AKDM4EPDE4B | |
| SCHEMBL21342417 | 0.83 | KDM1A (0.43) | LMNAMAPTKDM1AKDM4ETP53 | |
| SCHEMBL21342018 | 0.81 | KDM1A (0.47) | KDM1APDE4B | |
| SCHEMBL21342410 | 0.81 | KDM1A (0.47) | KDM1APDE4B | |
| SCHEMBL20001277 | 0.80 | FPR1 (0.63) | KDM1APDE4BALDH1A1 | |
| SCHEMBL19988380 | 0.80 | FPR1 (0.63) | KDM1APDE4BALDH1A1 | |
| SCHEMBL15091433 | 0.79 | KDM1A (0.76) | KDM1APDE4BSMN1; SMN2 | |
| SCHEMBL15091431 | 0.79 | KDM1A (0.76) | KDM1APDE4BSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019170904-A1 | PIPERIDINES OR PIPERIDONES SUBSTITUTED WITH UREA AND PHENYL | Grünenthal GmbH (DE) | 2019-09-12 | — | — | WO | disclosed |