SCHEMBL213433

SCHEMBL213433

CCOc1ccc(N)cc1N

nearest known ligand 0.69

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 6/20 0.69
ALDH1A1 P00352 4/20 0.69
KDM4E B2RXH2 3/20 0.69
GAA P10253 3/20 0.69
POLB P06746 3/20 0.69
MEN1 O00255 3/20 0.69
KMT2A Q03164 3/20 0.69
TP53 P04637 3/20 0.69
USP2 O75604 2/20 0.69
CASP1 P29466 2/20 0.69
ATM Q13315 2/20 0.69
HTT P42858 1/20 0.69
CASP7 P55210 1/20 0.69
HSD17B10 Q99714 2/20 0.59
NPC1 O15118 1/20 0.59
RAB9A P51151 1/20 0.59
SMN1; SMN2 Q16637 1/20 0.59
CREBBP Q92793 1/20 0.58
L3MBTL1 Q9Y468 2/20 0.53
HPGD P15428 1/20 0.53

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30678626 1.00 MAPT (0.69) MAPTALDH1A1KDM4EGAAPOLB
Hydrochloric Acid SCHEMBL2289247 0.98 MAPT (0.72) MAPTALDH1A1KDM4EGAAPOLB
Sulfuric Acid SCHEMBL31194868 0.89 HSD17B10 (0.58) MAPTALDH1A1KDM4EGAAPOLB
Sulfuric Acid SCHEMBL7105343 0.89 HSD17B10 (0.58) MAPTALDH1A1KDM4EGAAPOLB
Sulfuric Acid SCHEMBL3332113 0.89 HSD17B10 (0.58) MAPTALDH1A1KDM4EGAAPOLB
SCHEMBL28122689 0.86 MAPT (0.63) MAPTALDH1A1KDM4EGAAPOLB
SCHEMBL7134481 0.86 ALDH1A1 (0.58) MAPTALDH1A1KDM4EGAAPOLB
SCHEMBL112468 0.84 MAPT (0.78) MAPTALDH1A1KDM4EGAAPOLB
SCHEMBL31095359 0.84 MAPT (0.78) MAPTALDH1A1KDM4EGAAPOLB
SCHEMBL3789389 0.84 MAPT (0.61) MAPTALDH1A1KDM4EGAAPOLB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1026 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-117696019-A Plant fiber-based adsorption material and preparation method and application thereof 中国科学院赣江创新研究院 2024-03-15 CN claimed
CN-111269135-A Production process of 2-amino-4-acetamidophenyl ether 中卫市鑫三元化工有限公司 2020-06-12 CN claimed
US-10639257-B2 Composition for colouring keratin fibres BEAUTY & BUSINESS S.P.A. (IT) 2020-05-05 US claimed
CN-110158407-A A kind of graphene conductive antiskid abrasion performance road surface and its construction method 山东交通学院 2019-08-23 CN claimed
US-20190117541-A1 COMPOSITION FOR COLOURING KERATIN FIBRES BEAUTY & BUSINESS S.P.A. (IT) 2019-04-25 US claimed
US-9993413-B2 Keratin fibre dyeing composition BEAUTY & BUSINESS S.P.A. (IT) 2018-06-12 US claimed
US-20170258695-A1 KERATIN FIBRE DYEING COMPOSITION BEAUTY & BUSINESS S.P.A. (IT) 2017-09-14 US claimed
US-8043385-B2 Composition oxidation colouring of keratinic fibres, containing a cationic cellulose ether, a metasilicate and oxidation dyes, method for oxidation colouring and uses thereof L'OREAL S.A. (FR) 2011-10-25 US claimed
US-8002847-B2 Composition for oxidation dyeing keratin fibres comprising a cationic cellulose ether, a weakly oxyethylenated sorbitan fatty acid ester and oxidation dyes L 'OREAL S.A. (FR) 2011-08-23 US claimed
US-20110020251-A1 Ultraviolet-Absorbing Compounds AVOCA LLC 2011-01-27 US claimed
US-4713080-A OXIDATIVE COLORING WELLA AKTIENGESELLSCHAFT (DE) 1987-12-15 US claimed
EP-0166155-B1 2-ALKYLSULPHONYL-1,4-DIAMINOBENZENES, PROCESS FOR THEIR PREPARATION AND OXIDATIVE HAIR-DYEING COMPOSITIONS CONTAINING THESE COMPOUNDS Wella Aktiengesellschaft (DE) 1987-09-23 EP claimed
EP-0226072-A1 Oxidation dye containing 4-amino-2-aminomethyl phenol Wella Aktiengesellschaft (DE) 1987-06-24 EP claimed
WO-1987003475-A2 OXIDIZING HAIR DYER BASED ON 4-AMINO-2-AMINOMETHYLPHENOLS WELLA AKTIENGESELLSCHAFT (DE) 1987-06-18 WO claimed
US-4661114-A COUPLERS WELLA AKTIENGESELLSCHAFT (DE) 1987-04-28 US claimed
EP-0182187-A1 Oxidative dyestuff compositions for dyeing the hair, consisting of 4-amino-2-hydroxyalkyl phenols Wella Aktiengesellschaft (DE) 1986-05-28 EP claimed
WO-1986000303-A1 TWO-ALKYL-SULPHONYL-1,4-DIAMINOBENZENES, PREPARATION THEREOF AND UTILISATION THEREOF WELLA AKTIENGESELLSCHAFT (DE) 1986-01-16 WO claimed
EP-0166155-A1 2-Alkylsulphonyl-1,4-diaminobenzenes, process for their preparation and oxidative hair-dyeing compositions containing these compounds Wella Aktiengesellschaft (DE) 1986-01-02 EP claimed
US-4473375-A COUPLER AND DEVELOPER FOR OXIDATION COLOR DYES WELLA AKTIENGESELLSCHAFT (DE) 1984-09-25 US claimed
US-4107151-A FROM POLYISOCYANATE, CHAIN POLYOL, AROMATIC DIAMINE, POLYOL OR AMINO ALCOHOL WITH URETHANE BOND IHARA CHEMICAL COMPANY CO., LTD. (JP) 1978-08-15 US claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110020251-A1 Ultraviolet-Absorbing Compounds UFM1, UHRF1, CUTA MAPT 322/4885ALDH1A1 152/4885KDM4E 135/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.