SCHEMBL21343398

SCHEMBL21343398

CC1(C)c2cc(Cl)ccc2-c2c1c1c(c3c2oc2ccccc23)-c2ccccc2C1(C)C

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
AHR P35869 5/20 0.38
IDO1 P14902 2/20 0.36
PGR P06401 2/20 0.34
ALOX5 P09917 2/20 0.34
MAOA P21397 1/20 0.34
PDK2 Q15119 1/20 0.33
MEN1 O00255 1/20 0.33
POLB P06746 1/20 0.33
KMT2A Q03164 1/20 0.33
LMNA P02545 1/20 0.33
MAPT P10636 1/20 0.33
IGF1R P08069 1/20 0.32
MAPK1 P28482 1/20 0.32
SMN1; SMN2 Q16637 1/20 0.32
GABRP O00591 1/20 0.32
GABRD O14764 1/20 0.32
GABRA1 P14867 1/20 0.32
GABRB1 P18505 1/20 0.32
GABRG2 P18507 1/20 0.32
GABRB3 P28472 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21343243 1.00 AHR (0.38) AHRIDO1PGRALOX5MAOA
SCHEMBL21794251 0.92 AHR (0.33) AHRIDO1PGRALOX5MAOA
SCHEMBL21343399 0.92 AHR (0.33) AHRIDO1ALOX5PDK2MEN1
SCHEMBL21785388 0.92 AHR (0.33) AHRIDO1ALOX5PDK2MEN1
SCHEMBL21343240 0.90 AHR (0.35) AHRIDO1ALOX5MEN1POLB
SCHEMBL21350243 0.90 AHR (0.35) AHRIDO1ALOX5MEN1POLB
SCHEMBL21343397 0.89 ALOX5 (0.35) PGRALOX5MAOAMEN1KMT2A
SCHEMBL21344437 0.86 ALOX5 (0.36) ALOX5
SCHEMBL22859813 0.85 ALOX5 (0.34) ALOX5
SCHEMBL21350255 0.83 ALK (0.33) ALOX5PDK2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20220204520-A1 MATERIALS FOR ORGANIC ELECTROLUMINESCENT DEVICES MERCK PATENT GMBH (DE) 2022-06-30 US disclosed
EP-3844242-B1 MATERIALS FOR ORGANIC ELECTROLUMINESCENT DEVICES MERCK PATENT GMBH (DE) 2022-06-22 EP disclosed
US-20220140248-A1 MATERIALS FOR ORGANIC ELECTROLUMINESCENT DEVICES MERCK PATENT GMBH (DE) 2022-05-05 US disclosed
US-20210005821-A1 MATERIALS FOR ORGANIC ELECTROLUMINESCENT DEVICES MERCK PATENT GMBH (DE) 2021-01-07 US disclosed
WO-2020043640-A1 MATERIALS FOR ORGANIC ELECTROLUMINESCENT DEVICES MERCK PATENT GMBH (DE) 2020-03-05 WO disclosed
WO-2020043657-A1 MATERIALS FOR ORGANIC ELECTROLUMINESCENT DEVICES MERCK PATENT GMBH (DE) 2020-03-05 WO disclosed
WO-2019170578-A1 MATERIALS FOR ORGANIC ELECTROLUMINESCENT DEVICES MERCK PATENT GMBH (DE) 2019-09-12 WO disclosed
WO-2019170572-A1 MATERIALS FOR ORGANIC ELECTROLUMINESCENT DEVICES MERCK PATENT GMBH (DE) 2019-09-12 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20220204520-A1 MATERIALS FOR ORGANIC ELECTROLUMINESCENT DEVICES L1CAM, EFNA1, EPCAM AHR 3734/4885IDO1 2247/4885PGR 2032/4885
US-20210005821-A1 MATERIALS FOR ORGANIC ELECTROLUMINESCENT DEVICES L1CAM, EFNA1, EPCAM AHR 3734/4885IDO1 2247/4885PGR 2032/4885
US-20220140248-A1 MATERIALS FOR ORGANIC ELECTROLUMINESCENT DEVICES L1CAM, EFNA1, EPCAM AHR 3734/4885IDO1 2247/4885PGR 2032/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.