Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 4/20 | 0.39 |
| ▸ | GRM4 | Q14833 | 4/20 | 0.38 |
| ▸ | NPC1 | O15118 | 2/20 | 0.38 |
| ▸ | RAB9A | P51151 | 2/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | PKM | P14618 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22942059 | 0.89 | RAB9A (0.35) | GAAGRM4NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL21361250 | 0.89 | MAOB (0.38) | GRM4NPC1RAB9ASMN1; SMN2KMT2A | |
| SCHEMBL21361231 | 0.88 | TNKS2 (0.36) | GRM4NPC1RAB9ASMN1; SMN2LMNA | |
| SCHEMBL21344830 | 0.85 | FAAH (0.41) | NPC1RAB9ASMN1; SMN2HSD17B10MAPT | |
| SCHEMBL21361295 | 0.84 | GPR6 (0.37) | GRM4NPC1RAB9ASMN1; SMN2HSD17B10 | |
| SCHEMBL22992067 | 0.83 | GRM4 (0.38) | GRM4NPC1RAB9ASMN1; SMN2HSD17B10 | |
| SCHEMBL22859737 | 0.83 | KCNH2 (0.38) | GRM4MAPTPOLB | |
| SCHEMBL22908556 | 0.82 | GRM4 (0.37) | GRM4ALDH1A1 | |
| SCHEMBL24120293 | 0.80 | RAB9A (0.38) | GAAGRM4NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL24120381 | 0.79 | MAOB (0.39) | GAAGRM4NPC1RAB9ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019170745-A1 | HERBICIDAL COMPOUNDS | SYNGENTA PARTICIPATIONS AG (CH) | 2019-09-12 | — | — | WO | disclosed |