Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 5/20 | 0.34 |
| ▸ | USP2 | O75604 | 2/20 | 0.34 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.34 |
| ▸ | NNMT | P40261 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.32 |
| ▸ | GPR183 | P32249 | 1/20 | 0.32 |
| ▸ | ACACA | Q13085 | 3/20 | 0.31 |
| ▸ | ACACB | O00763 | 1/20 | 0.31 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.31 |
| ▸ | ABCC1 | P33527 | 1/20 | 0.31 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.31 |
| ▸ | SLCO1B1 | Q9Y6L6 | 1/20 | 0.31 |
| ▸ | TRPC6 | Q9Y210 | 2/20 | 0.31 |
| ▸ | GRM3 | Q14832 | 1/20 | 0.31 |
| ▸ | CCR8 | P51685 | 1/20 | 0.30 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.30 |
| ▸ | SCD | O00767 | 1/20 | 0.30 |
| ▸ | SCD5 | Q86SK9 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24120373 | 0.91 | NNMT (0.34) | NNMTGABRA1SCDSCD5 | |
| SCHEMBL22908445 | 0.88 | CYP3A4 (0.34) | CYP3A4USP2CYP2D6NNMTCYP1A2 | |
| SCHEMBL21344262 | 0.88 | KCNK3 (0.36) | CYP3A4USP2CYP2D6ACACAACACB | |
| SCHEMBL24120355 | 0.87 | NNMT (0.33) | NNMTGABRA1SCDSCD5 | |
| SCHEMBL21343892 | 0.86 | DRD3 (0.43) | CYP3A4USP2CYP2D6CYP1A2TSHR | |
| SCHEMBL22992070 | 0.86 | CYP3A4 (0.33) | CYP3A4USP2CYP2D6CYP1A2TSHR | |
| SCHEMBL22992042 | 0.85 | NAMPT (0.37) | CYP3A4CYP2D6CYP1A2TSHRACACA | |
| SCHEMBL21344681 | 0.84 | CYP1A2 (0.38) | CYP3A4USP2CYP2D6CYP1A2TSHR | |
| SCHEMBL21344729 | 0.84 | ACACA (0.33) | GABRA1ACACAACACB | |
| SCHEMBL21344269 | 0.84 | TSHR (0.47) | CYP3A4USP2CYP2D6CYP1A2TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-12043599-B2 | Herbicidal compounds | SYNGENTA PARTICIPATIONS AG (CH) | 2024-07-23 | — | — | US | disclosed |
| US-12043599-B2 | Herbicidal compounds | SYNGENTA PARTICIPATIONS AG (CH) | 2024-07-23 | — | — | US | disclosed |
| EP-3762378-B1 | HERBICIDAL COMPOUNDS | SYNGENTA PARTICIPATIONS AG (CH) | 2022-05-18 | — | — | EP | disclosed |
| US-20210047274-A1 | HERBICIDAL COMPOUNDS | SYNGENTA PARTICIPATIONS AG (CH) | 2021-02-18 | — | — | US | disclosed |
| WO-2019170745-A1 | HERBICIDAL COMPOUNDS | SYNGENTA PARTICIPATIONS AG (CH) | 2019-09-12 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210047274-A1 | HERBICIDAL COMPOUNDS | DDT, CBR3, GLRX3 | CYP3A4 245/4885USP2 2071/4885CYP2D6 120/4885 |
| US-12043599-B2 | Herbicidal compounds | DDT, CBR3, GLRX3 | CYP3A4 245/4885USP2 2071/4885CYP2D6 120/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.