SCHEMBL21343983

SCHEMBL21343983

CC1(C)c2cc(Br)ccc2-c2c1c1c(c3c2oc2ccccc23)-c2ccc(Br)cc2C1(C)C

nearest known ligand 0.35

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
NMUR2 Q9GZQ4 2/20 0.35
ALOX5 P09917 1/20 0.34
GABRP O00591 1/20 0.33
GABRD O14764 1/20 0.33
GABRA1 P14867 1/20 0.33
GABRB1 P18505 1/20 0.33
GABRG2 P18507 1/20 0.33
GABRB3 P28472 1/20 0.33
GABRA5 P31644 1/20 0.33
GABRA3 P34903 1/20 0.33
GABRA2 P47869 1/20 0.33
GABRB2 P47870 1/20 0.33
GABRA4 P48169 1/20 0.33
GABRE P78334 1/20 0.33
GABRA6 Q16445 1/20 0.33
GABRG1 Q8N1C3 1/20 0.33
GABRG3 Q99928 1/20 0.33
GABRQ Q9UN88 1/20 0.33
EGFR P00533 1/20 0.33
IDO1 P14902 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21343240 0.93 AHR (0.35) NMUR2ALOX5GABRPGABRDGABRA1
SCHEMBL21350243 0.93 AHR (0.35) NMUR2ALOX5GABRPGABRDGABRA1
SCHEMBL19110415 0.86 NMUR2 (0.34) NMUR2ALOX5GABRPGABRDGABRA1
SCHEMBL21343397 0.84 ALOX5 (0.35) ALOX5ALKMAOAMEN1CYP2C19
SCHEMBL21343242 0.84 NMUR2 (0.34) NMUR2ALOX5GABRPGABRDGABRA1
SCHEMBL22004808 0.84 NMUR2 (0.34) NMUR2ALOX5GABRPGABRDGABRA1
SCHEMBL21343243 0.82 AHR (0.38) ALOX5GABRPGABRDGABRA1GABRB1
SCHEMBL21343398 0.82 AHR (0.38) ALOX5GABRPGABRDGABRA1GABRB1
SCHEMBL21344312 0.82 CDC14B (0.35) ALOX5ALKMEN1KMT2A
SCHEMBL21344437 0.82 ALOX5 (0.36) ALOX5ALK

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2024115426-A1 POLYMERS CONTAINING SPIROTRUXENE DERIVATIVES AS THE REPEATING UNITS, AND ELECTROLUMINESCENT DEVICES CONTAINING SAID POLYMERS MERCK PATENT GMBH (DE) 2024-06-06 WO disclosed
WO-2019170572-A1 MATERIALS FOR ORGANIC ELECTROLUMINESCENT DEVICES MERCK PATENT GMBH (DE) 2019-09-12 WO disclosed
WO-2019170578-A1 MATERIALS FOR ORGANIC ELECTROLUMINESCENT DEVICES MERCK PATENT GMBH (DE) 2019-09-12 WO disclosed