SCHEMBL21345261

SCHEMBL21345261

NOCc1ccc(SSc2ccc(CBr)cc2)cc1

nearest known ligand 0.52

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
IDO1 P14902 17/20 0.52
AGXT P21549 11/20 0.47
CYP3A4 P08684 2/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL509145 0.82 TRPA1 (0.48)
SCHEMBL438248 0.75 IDO1 (0.78) IDO1AGXTCYP3A4
SCHEMBL12337678 0.72 ALDH1A1 (0.39) IDO1
SCHEMBL21088432 0.69 TRPA1 (0.43)
SCHEMBL1714667 0.69 IDO1 (1.00) IDO1AGXTCYP3A4
SCHEMBL7561792 0.68 TSHR (0.48) CYP3A4
SCHEMBL945021 0.67 AGXT (0.37) IDO1AGXT
Hydrochloric Acid SCHEMBL1715822 0.67 IDO1 (1.00) IDO1AGXTCYP3A4
SCHEMBL9674968 0.67 IDO1 (0.50) IDO1AGXTCYP3A4
Hydrochloric Acid SCHEMBL5531055 0.67 PTPRZ1 (0.62) IDO1AGXTCYP3A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2019169953-A1 CD24-TARGETING MONOCLONAL ANTIBODY AND DIETHYLAMINE AZO ONIUM DIOL SALT CONJUGATE AND USE THEREOF 中国药科大学 2019-09-12 WO disclosed