Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM1A | O60341 | 1/20 | 0.52 |
| ▸ | MAOA | P21397 | 1/20 | 0.52 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 4/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.40 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.40 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.40 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.40 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | EED | O75530 | 1/20 | 0.38 |
| ▸ | SUZ12 | Q15022 | 1/20 | 0.38 |
| ▸ | EZH2 | Q15910 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13408002 | 0.84 | KDM1A (0.54) | KDM1AMAOAL3MBTL1KMT2AMEN1 | |
| SCHEMBL20084008 | 0.80 | GAA (0.41) | L3MBTL1KMT2AMEN1MAPK1SMN1; SMN2 | |
| SCHEMBL28072832 | 0.79 | L3MBTL1 (0.46) | KDM1AMAOAL3MBTL1KMT2AMEN1 | |
| SCHEMBL21601057 | 0.79 | KDM1A (0.50) | KDM1AMAOAL3MBTL1KMT2AMEN1 | |
| SCHEMBL18901136 | 0.79 | ROCK2 (0.41) | KDM1AMAOAL3MBTL1KMT2AMEN1 | |
| SCHEMBL8418210 | 0.77 | L3MBTL1 (0.47) | KDM1AMAOAL3MBTL1KMT2AMEN1 | |
| SCHEMBL4657734 | 0.76 | KDM1A (0.47) | KDM1AMAOAL3MBTL1KMT2AMEN1 | |
| SCHEMBL24685480 | 0.76 | L3MBTL1 (0.46) | KDM1AMAOAL3MBTL1KMT2AMEN1 | |
| SCHEMBL696401 | 0.76 | L3MBTL1 (0.46) | KDM1AMAOAL3MBTL1KMT2AMEN1 | |
| SCHEMBL178447 | 0.76 | L3MBTL1 (0.46) | KDM1AMAOAL3MBTL1KMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019170086-A1 | ACYL-SUBSTITUTED OXAZINO-QUINAZOLINE COMPOUND, PREPARATION METHOD THEREFOR, AND USES THEREOF | 北京赛特明强医药科技有限公司 | 2019-09-12 | — | — | WO | disclosed |