Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2132754 | 1.00 | HTR3A (0.58) | HTR3AKCNH2 | |
| SCHEMBL262855 | 1.00 | HTR3A (0.58) | HTR3AKCNH2 | |
| Hydrochloric Acid SCHEMBL261222 | 0.99 | HTR3A (0.57) | HTR3AKCNH2 | |
| Hydrochloric Acid SCHEMBL260338 | 0.99 | HTR3A (0.57) | HTR3AKCNH2 | |
| Hydrochloric Acid SCHEMBL260652 | 0.99 | HTR3A (0.57) | HTR3AKCNH2 | |
| SCHEMBL263543 | 0.82 | HTR3A (0.53) | HTR3A | |
| SCHEMBL280581 | 0.82 | HTR3A (0.53) | HTR3A | |
| SCHEMBL280532 | 0.82 | HTR3A (0.53) | HTR3A | |
| Hydrochloric Acid SCHEMBL260277 | 0.81 | HTR3A (0.52) | HTR3A | |
| Hydrochloric Acid SCHEMBL260497 | 0.81 | HTR3A (0.52) | HTR3A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8252811-B2 | Indazoles, benzothiazoles, and benzoisothiazoles, and preparation and uses thereof | MEMORY PHARMACEUTICALS CORPORATION (US) | 2012-08-28 | — | — | US | claimed |
| US-20120101094-A1 | INDAZOLES, BENZOTHIAZOLES, AND BENZOISOTHIAZOLES, AND PREPARATION AND USES THEREOF | XIE WENGE (US) | 2012-04-26 | — | — | US | claimed |
| US-20040132790-A1 | Indazoles, benzothiazoles, and benzoisothiazoles, and preparation and uses thereof | MEMORY PHARMACEUTICALS CORPORATION | 2004-07-08 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120101094-A1 | INDAZOLES, BENZOTHIAZOLES, AND BENZOISOTHIAZOLES, AND PREPARATION AND USES THEREOF | CHRNA7, CHRNA5, CHRNA3 | HTR3A 152/4885KCNH2 331/4885 |
| US-20040132790-A1 | Indazoles, benzothiazoles, and benzoisothiazoles, and preparation and uses thereof | CHRNA5, CHRNA7, CHRNA3 | HTR3A 166/4885KCNH2 490/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.