SCHEMBL21346932

SCHEMBL21346932

Cc1cc(CCc2ccc(I)c(C)c2)ccc1I

nearest known ligand 0.41

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
PTGS1 P23219 1/20 0.41
PTGS2 P35354 1/20 0.41
SKP2 Q13309 1/20 0.41
ESR1 P03372 1/20 0.38
ESR2 Q92731 1/20 0.38
DAO P14920 2/20 0.35
S1PR1 P21453 1/20 0.33
TAAR5 O14804 1/20 0.33
TAAR1 Q96RJ0 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL26586595 0.87 SKP2 (0.36) PTGS1PTGS2SKP2ESR1ESR2
SCHEMBL19154351 0.85 ESR1 (0.54) PTGS1PTGS2SKP2ESR1ESR2
SCHEMBL4421807 0.85 SKP2 (0.61) PTGS1PTGS2SKP2ESR1
SCHEMBL21360878 0.84 PTGS1 (0.36) PTGS1PTGS2SKP2DAOTAAR1
SCHEMBL8065786 0.83 TRPA1 (0.43) PTGS1PTGS2SKP2ESR1ESR2
SCHEMBL25220929 0.82 SKP2 (0.53) PTGS1PTGS2SKP2ESR1
SCHEMBL9745264 0.82 SKP2 (0.33) PTGS1PTGS2SKP2ESR1ESR2
SCHEMBL17471730 0.82 BCHE (0.42) SKP2
SCHEMBL171208 0.81 ESR1 (0.40) PTGS1PTGS2ESR1ESR2S1PR1
SCHEMBL30831846 0.81 ESR1 (0.35) PTGS1PTGS2SKP2ESR1ESR2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10915020-B2 Photosensitive resin composition, photosensitive resin layer using same and color filter SAMSUNG SDI CO., LTD. (KR) 2021-02-09 US disclosed
US-20190278177-A1 PHOTOSENSITIVE RESIN COMPOSITION, PHOTOSENSITIVE RESIN LAYER USING SAME AND COLOR FILTER SAMSUNG SDI CO., LTD. (KR) 2019-09-12 US disclosed