SCHEMBL9745264

SCHEMBL9745264

Cc1cc(CC[Si](C)(C)I)ccc1I

nearest known ligand 0.33

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
SKP2 Q13309 1/20 0.33
ESR1 P03372 1/20 0.31
ESR2 Q92731 1/20 0.31
PTGS1 P23219 1/20 0.30
PTGS2 P35354 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21346932 0.82 PTGS1 (0.41) SKP2ESR1ESR2PTGS1PTGS2
SCHEMBL26586595 0.75 SKP2 (0.36) SKP2ESR1ESR2PTGS1PTGS2
SCHEMBL17471730 0.74 BCHE (0.42) SKP2
SCHEMBL19154351 0.73 ESR1 (0.54) SKP2ESR1ESR2PTGS1PTGS2
SCHEMBL4421807 0.73 SKP2 (0.61) SKP2ESR1PTGS1PTGS2
SCHEMBL8065786 0.71 TRPA1 (0.43) SKP2ESR1ESR2PTGS1PTGS2
SCHEMBL25220929 0.70 SKP2 (0.53) SKP2ESR1PTGS1PTGS2
SCHEMBL171208 0.70 ESR1 (0.40) ESR1ESR2PTGS1PTGS2
SCHEMBL20549337 0.70 ESR1 (0.35) SKP2ESR1ESR2PTGS1PTGS2
SCHEMBL24219430 0.70 HRH3 (0.39) SKP2ESR1ESR2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5156918-A SELF-ASSEMBLED SUPER LATTICES NORTHWESTERN UNIVERSITY (US) 1992-10-20 US disclosed