SCHEMBL2134705

SCHEMBL2134705

C=Cc1ccc2ccc3ncccc3c2n1

nearest known ligand 0.61

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LMNA P02545 3/20 0.61
CYP3A4 P08684 2/20 0.49
MAPT P10636 4/20 0.48
KDM4E B2RXH2 4/20 0.48
HSP90AA1 P07900 3/20 0.40
MEN1 O00255 3/20 0.40
KMT2A Q03164 3/20 0.40
HTT P42858 2/20 0.40
HIF1A Q16665 2/20 0.40
HSP90AB1 P08238 1/20 0.40
BLM P54132 1/20 0.40
SMN1; SMN2 Q16637 3/20 0.39
CCR1 P32246 3/20 0.39
TDP1 Q9NUW8 2/20 0.39
CCR5 P51681 2/20 0.39
CCR8 P51685 2/20 0.39
GMNN O75496 1/20 0.39
TP53 P04637 1/20 0.39
MMP2 P08253 1/20 0.39
CYP2D6 P10635 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12068202 0.83 LMNA (0.61) LMNACYP3A4MAPTKDM4EHSP90AA1
SCHEMBL27788690 0.80 LMNA (0.56) LMNACYP3A4MAPTKDM4EHSP90AA1
SCHEMBL17127162 0.79 CCR1 (0.61) LMNACYP3A4MAPTKDM4EHSP90AA1
SCHEMBL31301044 0.77 LMNA (0.67) LMNACYP3A4MAPTKDM4EHSP90AA1
SCHEMBL899929 0.77 ALDH1A1 (0.45) LMNACYP3A4MAPTKDM4EHSP90AA1
SCHEMBL322128 0.76 LMNA (0.56) LMNACYP3A4MAPTKDM4EHSP90AA1
SCHEMBL6513577 0.76 LMNA (1.00) LMNACYP3A4MAPTKDM4EHSP90AA1
SCHEMBL8313 0.76 LMNA (1.00) LMNACYP3A4MAPTKDM4EHSP90AA1
SCHEMBL9860875 0.75 LMNA (0.69) LMNACYP3A4MAPTKDM4EHSP90AA1
Iodide SCHEMBL10638043 0.74 LMNA (0.96) LMNACYP3A4MAPTKDM4EHSP90AA1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 27 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-117551249-A Vinyl phenanthroline covalent organic framework material and preparation method and application thereof 河北工业大学 2024-02-13 CN claimed
CN-109148796-B Acid scavenging functional diaphragm for lithium ion electrochemical cell functional performance 通用汽车环球科技运作有限责任公司 2022-01-25 CN claimed
US-10741812-B2 Acid-scavenging functional separators for power performance of lithium ion electrochemical cells GM Global Technology Operations LLC (US) 2020-08-11 US claimed
CN-109148796-A Acid for lithium ion electrochemical cells power-performance removes function diaphragm 通用汽车环球科技运作有限责任公司 2019-01-04 CN claimed
US-20180366781-A1 ACID-SCAVENGING FUNCTIONAL SEPARATORS FOR POWER PERFORMANCE OF LITHIUM ION ELECTROCHEMICAL CELLS GM Global Technology Operations LLC 2018-12-20 US claimed
JP-8325204-A None JP disclosed
CN-117551249-A Vinyl phenanthroline covalent organic framework material and preparation method and application thereof 河北工业大学 2024-02-13 CN disclosed
CN-117551249-A Vinyl phenanthroline covalent organic framework material and preparation method and application thereof 河北工业大学 2024-02-13 CN disclosed
CN-117551249-A Vinyl phenanthroline covalent organic framework material and preparation method and application thereof 河北工业大学 2024-02-13 CN disclosed
WO-2023052225-A1 MEMBRANES FUJIFILM MANUFACTURING EUROPE BV (NL) 2023-04-06 WO disclosed
CN-109148796-B Acid scavenging functional diaphragm for lithium ion electrochemical cell functional performance 通用汽车环球科技运作有限责任公司 2022-01-25 CN disclosed
US-10741812-B2 Acid-scavenging functional separators for power performance of lithium ion electrochemical cells GM Global Technology Operations LLC (US) 2020-08-11 US disclosed
EP-1251346-B1 Sensors for the determination of organometallic compounds DYNASOL ELASTOMEROS SA (ES) 2008-10-15 EP disclosed
US-6875615-B2 Sensors for the determination of organometallic compounds DYNASOL ELASTOMEROS, S.A. (ES) 2005-04-05 US disclosed
EP-1251346-A1 Sensors for the determination of organometallic compounds Dynasol Elastomeros, S.A. (ES) 2002-10-23 EP disclosed
US-20020151081-A1 Sensors for the determination of organometallic compounds DYNASOL ELASTOMEROS, S.A. 2002-10-17 US disclosed
JP-H08325204-A PRODUCTION OF CARBONATE DAICEL CHEM IND LTD 1996-12-10 JP disclosed
EP-0729389-A1 MAGNETICALLY SEPARABLE CATALYSTS BASF AKTIENGESELLSCHAFT (DE) 1996-09-04 EP disclosed
WO-1995013874-A1 MAGNETICALLY SEPARABLE CATALYSTS BASF AKTIENGESELLSCHAFT (DE) 1995-05-26 WO disclosed
US-3980690-A Process for the carboxylation of alcohols in heterogeneous phase SNAMPROGETTI S.P.A. (IT) 1976-09-14 US disclosed