SCHEMBL2134708

SCHEMBL2134708

CC(C)(Cc1nc2ccccc2s1)S(N)(=O)=O

nearest known ligand 0.54

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ UBE2T Q9NPD8 1/20 0.54
▸ ASIC3 Q9UHC3 1/20 0.54
▸ SMN1; SMN2 Q16637 5/20 0.52
▸ NPC1 O15118 2/20 0.52
▸ RAB9A P51151 2/20 0.52
▸ CA12 O43570 1/20 0.51
▸ CA1 P00915 1/20 0.51
▸ CA2 P00918 1/20 0.51
▸ CA4 P22748 1/20 0.51
▸ CA7 P43166 1/20 0.51
▸ CA14 Q9ULX7 1/20 0.51
▸ KDM4E B2RXH2 2/20 0.49
▸ TDP1 Q9NUW8 1/20 0.49
▸ CYP1A2 P05177 2/20 0.48
▸ CYP2C19 P33261 2/20 0.48
▸ LOXL2 Q9Y4K0 1/20 0.48
▸ ALDH1A1 P00352 3/20 0.47
▸ HPGD P15428 2/20 0.47
▸ MEN1 O00255 2/20 0.47
▸ KMT2A Q03164 2/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10767668 0.82 UBE2T (0.62) UBE2TASIC3SMN1; SMN2NPC1RAB9A
SCHEMBL1691702 0.80 UBE2T (0.59) UBE2TASIC3SMN1; SMN2NPC1RAB9A
SCHEMBL11047151 0.78 SMN1; SMN2 (0.49) UBE2TASIC3SMN1; SMN2NPC1RAB9A
SCHEMBL15812327 0.78 UBE2T (0.62) UBE2TASIC3SMN1; SMN2NPC1RAB9A
SCHEMBL9065841 0.78 UBE2T (0.56) UBE2TASIC3SMN1; SMN2NPC1RAB9A
SCHEMBL1417362 0.77 UBE2T (0.56) UBE2TASIC3SMN1; SMN2NPC1RAB9A
SCHEMBL15671460 0.76 UBE2T (0.54) UBE2TASIC3SMN1; SMN2NPC1RAB9A
SCHEMBL29278084 0.75 UBE2T (0.49) UBE2TASIC3SMN1; SMN2NPC1RAB9A
SCHEMBL1272747 0.74 SMN1; SMN2 (0.67) UBE2TASIC3SMN1; SMN2NPC1RAB9A
SCHEMBL10367346 0.74 SMN1; SMN2 (0.71) UBE2TASIC3SMN1; SMN2NPC1RAB9A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 30 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2093078-B1 Method for producing a rubber mixture CONTINENTAL REIFEN DEUTSCHLAND (DE) 2012-04-25 — — EP claimed
EP-0713901-B1 Rubber composition SEMPERIT AG (AT) 1998-02-11 — — EP claimed
EP-0406214-B1 RUBBER COMPOSITION FORMING A DURABLE BOND TO COPPER ALLOYS DURING VULCANISATION AND USE THEREOF Semperit Reifen Aktiengesellschaft (AT) 1992-12-16 — — EP claimed
WO-2023165804-A1 PRESSED PRODUCTS MADE OF A CROSSLINKABLE MATERIAL, METHOD FOR THE PRODUCTION AND FURTHER PROCESSING THEREOF TO PRODUCE ELASTOMER-BASED MOULDED BODIES EVONIK OPERATIONS GMBH (DE) 2023-09-07 — — WO disclosed
WO-2023131515-A1 CROSSLINKABLE COMPOSITION BASED ON AN ELASTOMER-CONTAINING POWDER OR GRANULE, AND ELASTOMER COMPOUNDS AND ARTICLES OBTAINABLE THEREFROM EVONIK OPERATIONS GMBH (DE) 2023-07-13 — — WO disclosed
US-20230151190-A1 SULFUR-CROSSLINKABLE RUBBER-COATING MIXTURE CONTINENTAL REIFEN DEUTSCHLAND GMBH (DE) 2023-05-18 — — US disclosed
EP-4126560-A1 SULFUR-CROSSLINKABLE RUBBER-COATING MIXTURE Continental Reifen Deutschland GmbH (DE) 2023-02-08 — — EP disclosed
EP-4126561-A1 SULFUR-CROSSLINKABLE RUBBER-COATING MIXTURE Continental Reifen Deutschland GmbH (DE) 2023-02-08 — — EP disclosed
CN-115348924-A Sulfur-crosslinkable rubber coating mixture 大陆轮胎德国有限公司 2022-11-15 — — CN disclosed
CN-115348925-A Sulfur-crosslinkable rubber coating mixture 大陆轮胎德国有限公司 2022-11-15 — — CN disclosed
US-20210363333-A1 RUBBER BLEND, SULFUR-CROSSLINKABLE RUBBER MIXTURE, AND VEHICLE TIRE CONTINENTAL REIFEN DEUTSCHLAND GMBH (DE) 2021-11-25 — — US disclosed
US-6319993-B2 POLYMERIC CYCLOPENTANE POLYSULFIDES AND THEIR PREPARATION FOR DICYCLOPENTENYL POLYSULFIDES, SULFUR AND HYDROGEN SULFIDE; LOW COST REVERSION STABILIZERS BAYER AKTIENGESELLSCHAFT (DE) 2001-11-20 — — US disclosed
US-20010029290-A1 Vulcanizing agents for unsaturated rubber mixtures LANXESS DEUTSCHLAND GMBH (DE) 2001-10-11 — — US disclosed
US-6242534-B1 VULCANIZING RUBBER COMPONENT; A GEL FILLER MADE OF A RUBBER WITH SPECIFIC PARTICLE SIZE, SWELLING INDEX, ACID AND BASE GROUPS AND A SECOND GEL WHICH IS CAPABLE OF NEUTRALIZING THE FIRST GEL; IMPROVED HYSTERESIS AND GRIPPING CONTINENTAL AKTIENGESELLSCHAFT (DE) 2001-06-05 — — US disclosed
US-6133364-A VULCANIZABLE RUBBER MIXTURE CONSISTS OF A RUBBER COMPONENT, A FILLER, GEL PARTICLES COMPRISING RUBBER HAVING SPECIFIC PARTICLE SIZE WHOSE SURFACE HAS ELECTROPHILIC CENTERS, A SUBSTANCE ACTING AS A COUPLING AGENT CONTINENTAL AKTIENGESELLSCHAFT (DE) 2000-10-17 — — US disclosed
US-5859169-A PREPARED BY SIMULTANEOUS REACTION OF PHENOL, OXO COMPOUND, MONOMERIC URETHANE IN PRESENCE OF ACID CATALYST VIANORA RESINS GMBH (DE) 1999-01-12 — — US disclosed
US-5733944-A FREE-RADICAL POLYMERIZED LATEX FOAM RUBBER COMPRISES A COPOLYMER OF BUTADIENE OR ISOPRENE WITH ESTERS OF ACRYLIC OR METHACRYLIC ACID, CONTAINS ONLY HYDRATED INORGANIC SALTS AS FIRE RETRADANTS; MATTRESS, CUSHION OR UPHOLSTERY MATERIAL BASF AKTIENGESELLSCHAFT (DE) 1998-03-31 — — US disclosed
US-5259908-A Applying polybutadiene and metal salt hardening catalyst; forming washfast skin by oxygen exposure; vulcanization HENKEL KOMMANDITGESELLSCHAFT AUF AKTIEN (DE) 1993-11-09 — — US disclosed
US-5187232-A High modulus, high dynamic stress absorption BAYER AKTIENGESELLSCHAFT (DE) 1993-02-16 — — US disclosed
US-4437960-A SULFUR VULCANIZATION OF CATIONIC POLYMERS AKZO, N.V. (NL) 1984-03-20 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20010029290-A1 Vulcanizing agents for unsaturated rubber mixtures GGPS1, GSS, RNF168 UBE2T 1033/4885ASIC3 2457/4885SMN1; SMN2 3746/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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