SCHEMBL21347423

SCHEMBL21347423

c1ccc(-c2nc(-c3ccccc3)nc(-c3ccc(-n4c5ccccc5c5cc6c(cc54)c4ccccc4n6-c4ccc5c(c4)c4ccccc4n5-c4ccccc4)cc3)n2)cc1

nearest known ligand 0.51

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
L3MBTL1 Q9Y468 3/20 0.51
ATM Q13315 2/20 0.51
KDM4E B2RXH2 1/20 0.51
RAC2 P15153 1/20 0.41
RAC3 P60763 1/20 0.41
CDC42 P60953 1/20 0.41
RAC1 P63000 1/20 0.41
PTGER4 P35408 1/20 0.40
KMT2A Q03164 4/20 0.38
IL1R1 P14778 1/20 0.38
MEN1 O00255 3/20 0.37
ALDH1A1 P00352 2/20 0.37
MAPT P10636 2/20 0.37
HPGD P15428 1/20 0.37
HDAC4 P56524 1/20 0.37
HTT P42858 1/20 0.37
ABCG2 Q9UNQ0 1/20 0.37
RXRA P19793 1/20 0.36
AVPR1A P37288 1/20 0.36
PTPN1 P18031 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21365590 0.96 L3MBTL1 (0.50) L3MBTL1ATMKDM4ERAC2RAC3
SCHEMBL19269546 0.96 L3MBTL1 (0.52) L3MBTL1ATMKDM4ERAC2RAC3
SCHEMBL12093170 0.96 L3MBTL1 (0.52) L3MBTL1ATMKDM4ERAC2RAC3
SCHEMBL15583159 0.96 L3MBTL1 (0.52) L3MBTL1ATMKDM4ERAC2RAC3
SCHEMBL15786006 0.96 L3MBTL1 (0.52) L3MBTL1ATMKDM4ERAC2RAC3
SCHEMBL24677432 0.96 L3MBTL1 (0.52) L3MBTL1ATMKDM4ERAC2RAC3
SCHEMBL29559047 0.96 L3MBTL1 (0.52) L3MBTL1ATMKDM4ERAC2RAC3
SCHEMBL15371691 0.96 L3MBTL1 (0.52) L3MBTL1ATMKDM4ERAC2RAC3
SCHEMBL29775034 0.96 L3MBTL1 (0.52) L3MBTL1ATMKDM4ERAC2RAC3
SCHEMBL17278475 0.96 L3MBTL1 (0.56) L3MBTL1ATMKDM4ERAC2RAC3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3767698-B1 ORGANIC ELECTROLUMINESCENT ELEMENT NIPPON STEEL CHEMICAL & MAT CO LTD (JP) 2023-10-25 EP disclosed
US-20230320210-A1 HOST MATERIALS FOR ELECTROLUMINESCENT DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2023-10-05 US disclosed
US-20230320210-A1 HOST MATERIALS FOR ELECTROLUMINESCENT DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2023-10-05 US disclosed
US-11700766-B2 Host materials for electroluminescent devices UNIVERSAL DISPLAY CORPORATION (US) 2023-07-11 US disclosed
US-11700766-B2 Host materials for electroluminescent devices UNIVERSAL DISPLAY CORPORATION (US) 2023-07-11 US disclosed
US-11374178-B2 Organic electroluminescent element NIPPON STEEL CHEMICAL & MATERIAL CO., LTD. (JP) 2022-06-28 US disclosed
US-20220093876-A1 HOST MATERIALS FOR ELECTROLUMINESCENT DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2022-03-24 US disclosed
US-11217757-B2 Host materials for electroluminescent devices UNIVERSAL DISPLAY CORPORATION (US) 2022-01-04 US disclosed
US-20210119144-A1 ORGANIC ELECTROLUMINESCENT ELEMENT NIPPON STEEL CHEMICAL & MATERIAL CO., LTD. (JP) 2021-04-22 US disclosed
EP-3767698-A1 ORGANIC ELECTROLUMINESCENT ELEMENT NIPPON STEEL Chemical & Material Co., Ltd. (JP) 2021-01-20 EP disclosed
EP-3605634-A1 ORGANIC ELECTROLUMINESCENT ELEMENT NIPPON STEEL Chemical & Material Co., Ltd. (JP) 2020-02-05 EP disclosed
WO-2019176605-A1 ORGANIC ELECTROLUMINESCENT ELEMENT 日鉄ケミカル&マテリアル株式会社 2019-09-19 WO disclosed
US-20190280213-A1 HOST MATERIALS FOR ELECTROLUMINESCENT DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2019-09-12 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11700766-B2 Host materials for electroluminescent devices OR10J3, OCIAD2, MCM4 L3MBTL1 2241/4885ATM 4507/4885KDM4E 2981/4885
US-20220093876-A1 HOST MATERIALS FOR ELECTROLUMINESCENT DEVICES OR10J3, OCIAD2, MCM4 L3MBTL1 2241/4885ATM 4507/4885KDM4E 2981/4885
US-11217757-B2 Host materials for electroluminescent devices EML4, ELAVL1, ELAVL3 L3MBTL1 339/4885ATM 3699/4885KDM4E 2624/4885
US-20230320210-A1 HOST MATERIALS FOR ELECTROLUMINESCENT DEVICES OR10J3, OCIAD2, MCM4 L3MBTL1 2241/4885ATM 4507/4885KDM4E 2981/4885
US-20190280213-A1 HOST MATERIALS FOR ELECTROLUMINESCENT DEVICES EML4, ELAVL1, ELAVL3 L3MBTL1 339/4885ATM 3699/4885KDM4E 2624/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.