SCHEMBL21348174

SCHEMBL21348174

CCN(C)C(=O)OCc1ccc(C(C)C)cc1

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ MEN1 O00255 2/20 0.50
▸ KMT2A Q03164 2/20 0.50
▸ LMNA P02545 2/20 0.50
▸ IDO1 P14902 2/20 0.46
▸ RXRA P19793 1/20 0.46
▸ RXRB P28702 1/20 0.46
▸ PRSS1 P07477 1/20 0.44
▸ TPSAB1 Q15661 1/20 0.44
▸ NPC1 O15118 5/20 0.43
▸ RAB9A P51151 5/20 0.43
▸ L3MBTL1 Q9Y468 2/20 0.42
▸ BCHE P06276 2/20 0.42
▸ ACHE P22303 2/20 0.42
▸ FAAH O00519 1/20 0.42
▸ KDM4E B2RXH2 2/20 0.40
▸ POLB P06746 1/20 0.40
▸ SMN1; SMN2 Q16637 3/20 0.39
▸ EGFR P00533 1/20 0.39
▸ HPGD P15428 1/20 0.38
▸ HRH3 Q9Y5N1 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL24506203 0.88 NPC1 (0.44) MEN1KMT2ALMNAPRSS1TPSAB1
SCHEMBL26502414 0.86 MEN1 (0.49) MEN1KMT2ALMNAIDO1RXRA
SCHEMBL25978782 0.85 MEN1 (0.48) MEN1KMT2ALMNAIDO1RXRA
SCHEMBL15592194 0.85 MEN1 (0.51) MEN1KMT2ALMNAIDO1RXRA
SCHEMBL25749532 0.84 LMNA (0.46) MEN1KMT2ALMNAIDO1RXRA
SCHEMBL21896174 0.84 PRSS1 (0.49) LMNAPRSS1TPSAB1NPC1RAB9A
SCHEMBL21348178 0.84 MEN1 (0.47) MEN1KMT2ALMNAIDO1RXRA
SCHEMBL16015346 0.83 PRSS1 (0.48) MEN1KMT2ARXRARXRBPRSS1
SCHEMBL23489098 0.82 MEN1 (0.49) MEN1KMT2ALMNAIDO1RXRA
SCHEMBL16980507 0.82 MEN1 (0.68) MEN1KMT2ALMNARXRARXRB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20210170045-A1 RELEASABLE ANTIBODY CONJUGATES FISH & RICHARDSON PC 2021-06-10 — — US disclosed
WO-2019171358-A1 RELEASABLE ANTIBODY CONJUGATES QUIAPEG PHARMACEUTICALS AB (SE) 2019-09-12 — — WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20210170045-A1 RELEASABLE ANTIBODY CONJUGATES BCR, CD47, RNASE1 MEN1 775/4885KMT2A 2325/4885LMNA 3509/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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