SCHEMBL21349010

SCHEMBL21349010

O=c1c2ncn([C@@H]3O[C@H](COP(=O)(O)CP(=O)(O)O)[C@@H](O)[C@H]3O)c2ncn1Cc1ccccc1

nearest known ligand 0.69

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
TYMP P19971 1/20 0.69
NT5E P21589 17/20 0.67
PLCG1 P19174 1/20 0.62
ENPP1 P22413 1/20 0.62

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21839710 0.88 TYMP (0.71) TYMPNT5E
SCHEMBL23914896 0.88 TYMP (0.71) TYMPNT5E
SCHEMBL22843532 0.85 NT5E (0.57) TYMPNT5EPLCG1ENPP1
SCHEMBL27732293 0.83 TYMP (0.73) TYMP
SCHEMBL7615673 0.83 TYMP (0.73) TYMP
SCHEMBL5983454 0.83 TYMP (0.73) TYMP
SCHEMBL29393691 0.80 NT5E (1.00) NT5EPLCG1ENPP1
SCHEMBL23431307 0.80 NT5E (1.00) NT5EPLCG1ENPP1
SCHEMBL30394591 0.79 TYMP (0.58) TYMPNT5E
SCHEMBL22856824 0.78 NT5E (1.00) NT5E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2019173682-A1 PARENTERALLY ADMINISTERED IMMUNE ENHANCING DRUGS ARCUS BIOSCIENCES, INC. (US) 2019-09-12 WO disclosed