Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TYMP | P19971 | 4/20 | 0.73 |
| ▸ | SLC29A1 | Q99808 | 6/20 | 0.60 |
| ▸ | ADORA3 | P0DMS8 | 4/20 | 0.59 |
| ▸ | TP53 | P04637 | 1/20 | 0.59 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.59 |
| ▸ | STAT6 | P42226 | 1/20 | 0.59 |
| ▸ | ADORA1 | P30542 | 3/20 | 0.57 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.57 |
| ▸ | THPO | P40225 | 2/20 | 0.57 |
| ▸ | TSHR | P16473 | 2/20 | 0.57 |
| ▸ | ADORA2A | P29274 | 2/20 | 0.57 |
| ▸ | LMNA | P02545 | 2/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.56 |
| ▸ | GLA | P06280 | 1/20 | 0.56 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.56 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.56 |
| ▸ | NPC1 | O15118 | 1/20 | 0.56 |
| ▸ | NPY1R | P25929 | 1/20 | 0.56 |
| ▸ | HTT | P42858 | 1/20 | 0.56 |
| ▸ | NPY2R | P49146 | 1/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5983454 | 1.00 | TYMP (0.73) | TYMPSLC29A1ADORA3TP53TDP1 | |
| SCHEMBL27732293 | 1.00 | TYMP (0.73) | TYMPSLC29A1ADORA3TP53TDP1 | |
| SCHEMBL6765381 | 0.88 | SLC29A1 (0.62) | TYMPSLC29A1ADORA3TP53TDP1 | |
| SCHEMBL21839710 | 0.84 | TYMP (0.71) | TYMP | |
| SCHEMBL23914896 | 0.84 | TYMP (0.71) | TYMP | |
| SCHEMBL21349010 | 0.83 | TYMP (0.69) | TYMP | |
| SCHEMBL1533270 | 0.82 | ADORA3 (0.62) | SLC29A1ADORA3ADORA1ADORA2A | |
| SCHEMBL6882745 | 0.82 | ADORA3 (0.62) | SLC29A1ADORA3ADORA1ADORA2A | |
| SCHEMBL30074692 | 0.82 | TYMP (0.56) | TYMPSLC29A1ADORA3STAT6ADORA1 | |
| SCHEMBL31591198 | 0.79 | ADORA2A (0.53) | TYMPSLC29A1ADORA3TP53STAT6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1232166-A2 | SYNTHESIS OF 2'-DEOXY-L-NUCLEOSIDES | Pharmasset Limited (US) | 2002-08-21 | — | — | EP | disclosed |
| WO-2001034618-A2 | SYNTHESIS OF 2'-DEOXY-L-NUCLEOSIDES | PHARMASSET LIMITED (US) | 2001-05-17 | — | — | WO | disclosed |