Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TYMP | P19971 | 7/20 | 0.58 |
| ▸ | NT5E | P21589 | 10/20 | 0.43 |
| ▸ | DNPH1 | O43598 | 2/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21839710 | 0.80 | TYMP (0.71) | TYMPNT5E | |
| SCHEMBL23914896 | 0.80 | TYMP (0.71) | TYMPNT5E | |
| SCHEMBL21349010 | 0.79 | TYMP (0.69) | TYMPNT5E | |
| SCHEMBL5983454 | 0.78 | TYMP (0.73) | TYMP | |
| SCHEMBL27732293 | 0.78 | TYMP (0.73) | TYMP | |
| SCHEMBL7615673 | 0.78 | TYMP (0.73) | TYMP | |
| SCHEMBL30394512 | 0.76 | PRMT5 (0.48) | NT5EDNPH1 | |
| SCHEMBL5782783 | 0.76 | PRMT5 (0.48) | NT5EDNPH1 | |
| SCHEMBL30394498 | 0.74 | DNPH1 (0.49) | NT5EDNPH1 | |
| SCHEMBL30394824 | 0.74 | NT5E (0.56) | NT5EDNPH1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11591355-B2 | CD73 inhibitors and uses thereof | PELOTON THERAPEUTICS INC. (US) | 2023-02-28 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11591355-B2 | CD73 inhibitors and uses thereof | ENTPD5, ENTPD1, ENTPD3 | TYMP 28/4885NT5E 5/4885DNPH1 1090/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.