Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.34 |
| ▸ | PDE4A | P27815 | 2/20 | 0.33 |
| ▸ | PDE4B | Q07343 | 2/20 | 0.33 |
| ▸ | PDE4C | Q08493 | 2/20 | 0.33 |
| ▸ | PDE4D | Q08499 | 2/20 | 0.33 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | HPGD | P15428 | 2/20 | 0.31 |
| ▸ | HTT | P42858 | 2/20 | 0.31 |
| ▸ | GSK3A | P49840 | 1/20 | 0.31 |
| ▸ | GSK3B | P49841 | 1/20 | 0.31 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.30 |
| ▸ | KIT | P10721 | 1/20 | 0.30 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.30 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
| ▸ | GAA | P10253 | 1/20 | 0.30 |
| ▸ | MCOLN3 | Q8TDD5 | 1/20 | 0.30 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21339059 | 1.00 | ALDH1A1 (0.34) | ALDH1A1NPSR1PDE4APDE4BPDE4C | |
| SCHEMBL21339293 | 1.00 | ALDH1A1 (0.34) | ALDH1A1NPSR1PDE4APDE4BPDE4C | |
| SCHEMBL21339189 | 0.92 | ALDH1A1 (0.34) | ALDH1A1NPSR1PDE4APDE4BPDE4C | |
| SCHEMBL21338931 | 0.92 | ALDH1A1 (0.34) | ALDH1A1NPSR1PDE4APDE4BPDE4C | |
| SCHEMBL21338935 | 0.92 | ALDH1A1 (0.34) | ALDH1A1NPSR1PDE4APDE4BPDE4C | |
| SCHEMBL21338917 | 0.86 | ALDH1A1 (0.36) | ALDH1A1NPSR1PDE4APDE4BPDE4C | |
| SCHEMBL21338918 | 0.86 | ALDH1A1 (0.36) | ALDH1A1NPSR1PDE4APDE4BPDE4C | |
| SCHEMBL21339276 | 0.86 | ALDH1A1 (0.36) | ALDH1A1NPSR1PDE4APDE4BPDE4C | |
| SCHEMBL25021283 | 0.84 | ALDH1A1 (0.33) | ALDH1A1NPSR1SMN1; SMN2GSK3AGSK3B | |
| SCHEMBL21339315 | 0.84 | ALDH1A1 (0.33) | ALDH1A1NPSR1SMN1; SMN2GSK3AGSK3B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230049481-A1 | PICOLINAMIDES AS FUNGICIDES | DOW AGROSCIENCES LLC (US) | 2023-02-16 | — | — | US | disclosed |
| WO-2019173665-A1 | PICOLINAMIDES AS FUNGICIDES | DOW AGROSCIENCES LLC (US) | 2019-09-12 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230049481-A1 | PICOLINAMIDES AS FUNGICIDES | CYP1A2, CYP4F12, FKBP2 | ALDH1A1 1130/4885NPSR1 1327/4885PDE4A 2004/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.