Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC22A12 | Q96S37 | 17/20 | 0.52 |
| ▸ | ELANE | P08246 | 1/20 | 0.39 |
| ▸ | SLC22A6 | Q4U2R8 | 2/20 | 0.39 |
| ▸ | SLC2A9 | Q9NRM0 | 1/20 | 0.39 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | SLC22A11 | Q9NSA0 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21350907 | 0.88 | SLC22A12 (0.57) | SLC22A12SLC22A6SLC2A9ABCG2SLC22A11 | |
| SCHEMBL21350307 | 0.87 | ELANE (0.42) | SLC22A12ELANE | |
| SCHEMBL21350532 | 0.85 | ELANE (0.41) | SLC22A12ELANE | |
| SCHEMBL21350518 | 0.84 | CYP2C9 (0.45) | ELANEMAPTALDH1A1L3MBTL1 | |
| SCHEMBL21331887 | 0.83 | SLC22A12 (0.52) | SLC22A12ELANESLC22A6SLC2A9ABCG2 | |
| SCHEMBL21350629 | 0.83 | PDCD1 (0.42) | SLC22A12ELANE | |
| SCHEMBL21350752 | 0.82 | SLC22A12 (0.55) | SLC22A12SLC22A6SLC2A9ABCG2SLC22A11 | |
| SCHEMBL21350304 | 0.82 | SLC22A12 (0.52) | SLC22A12SLC22A6ABCG2MAPTTDP1 | |
| SCHEMBL21350621 | 0.81 | SLC22A12 (0.61) | SLC22A12SLC22A6SLC2A9ABCG2MAPT | |
| SCHEMBL21350635 | 0.77 | SLC22A12 (0.54) | SLC22A12SLC22A6ABCG2MAPTSLC22A11 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019169890-A1 | 3-(NAPHTHALENE-1-METHYL SUBSTITUTED)PYRIDINE DERIVATIVE, SYNTHETIC METHOD THEREFOR AND USE THEREOF | 南方医科大学 | 2019-09-12 | — | — | WO | disclosed |