Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC22A12 | Q96S37 | 18/20 | 0.52 |
| ▸ | SLC22A6 | Q4U2R8 | 4/20 | 0.39 |
| ▸ | ABCG2 | Q9UNQ0 | 3/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | SLC22A11 | Q9NSA0 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21350305 | 0.89 | SLC22A12 (0.57) | SLC22A12SLC22A6ABCG2SLC22A11 | |
| SCHEMBL21350531 | 0.87 | KDM4E (0.38) | SLC22A12MAPTKDM4E | |
| SCHEMBL21350306 | 0.85 | KDM4E (0.37) | SLC22A12MAPTKDM4E | |
| SCHEMBL21350514 | 0.83 | SLC22A12 (0.53) | SLC22A12SLC22A6MAPTSLC22A11KDM4E | |
| SCHEMBL21350517 | 0.82 | SLC22A12 (0.52) | SLC22A12SLC22A6ABCG2MAPTTDP1 | |
| SCHEMBL21350534 | 0.82 | SLC22A12 (0.56) | SLC22A12SLC22A6ABCG2SLC22A11 | |
| SCHEMBL21350621 | 0.82 | SLC22A12 (0.61) | SLC22A12SLC22A6ABCG2MAPTTDP1 | |
| SCHEMBL21350515 | 0.78 | SLC22A12 (0.59) | SLC22A12SLC22A6ABCG2SLC22A11 | |
| SCHEMBL21350635 | 0.78 | SLC22A12 (0.54) | SLC22A12SLC22A6ABCG2MAPTSLC22A11 | |
| SCHEMBL28408871 | 0.78 | POLB (0.43) | SLC22A12KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019169890-A1 | 3-(NAPHTHALENE-1-METHYL SUBSTITUTED)PYRIDINE DERIVATIVE, SYNTHETIC METHOD THEREFOR AND USE THEREOF | 南方医科大学 | 2019-09-12 | — | — | WO | disclosed |