SCHEMBL2135104

SCHEMBL2135104

COC(=O)c1sccc1S(=O)(=O)NC(=O)c1nc(C)nc(OC)n1

nearest known ligand 0.47

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
EDNRA P25101 5/20 0.47
MEN1 O00255 1/20 0.42
KMT2A Q03164 1/20 0.42
MAPT P10636 3/20 0.41
PPARG P37231 1/20 0.41
PPARD Q03181 1/20 0.41
PPARA Q07869 1/20 0.41
HPGD P15428 2/20 0.40
LMNA P02545 2/20 0.40
TSHR P16473 1/20 0.40
TAS2R8 Q9NYW2 1/20 0.39
SMN1; SMN2 Q16637 1/20 0.38
CCR2 P41597 1/20 0.37
TP53 P04637 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Thifensulfuron-Methyl SCHEMBL53606 0.83 EDNRA (0.46) EDNRAMEN1KMT2AMAPTPPARG
Thifensulfuron-Methyl SCHEMBL29463414 0.83 EDNRA (0.46) EDNRAMEN1KMT2AMAPTPPARG
Thifensulfuron-Methyl SCHEMBL20723624 0.83 EDNRA (0.46) EDNRAMEN1KMT2AMAPTPPARG
Thifensulfuron-Methyl SCHEMBL9139398 0.83 EDNRA (0.46) EDNRAMEN1KMT2AMAPTPPARG
Thifensulfuron-Methyl SCHEMBL2442597 0.79 EDNRA (0.43) EDNRAMEN1KMT2AMAPTPPARG
SCHEMBL8427062 0.79 EDNRA (0.42) EDNRAMEN1KMT2AMAPT
SCHEMBL10754403 0.77 EDNRA (0.47) EDNRAMEN1KMT2AMAPTPPARG
Thifensulfuron-Methyl SCHEMBL8522249 0.76 PPARG (0.41) EDNRAMEN1KMT2AMAPTPPARG
SCHEMBL10752070 0.76 EDNRA (0.50) EDNRAMEN1KMT2AMAPTPPARG
SCHEMBL2387020 0.76 ITGAV (0.35) LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7902118-B2 Herbicide and repellent adjuvant; reducing foliage retention; preventing damage to crops BOARD OF TRUSTEES OF MICHIGAN STATE UNIVERSITY (US) 2011-03-08 US disclosed
US-20050032645-A1 Compositions and methods for protecting cultivated plants from herbicidal injury BOARD OF TRUSTEES OF MICHIGAN STATE UNIVERSITY (US) 2005-02-10 US disclosed