Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADK | P55263 | 6/20 | 0.67 |
| ▸ | HSPA8 | P11142 | 4/20 | 0.44 |
| ▸ | HSPA5 | P11021 | 2/20 | 0.44 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.44 |
| ▸ | CDK5 | Q00535 | 1/20 | 0.44 |
| ▸ | CDK5R1 | Q15078 | 1/20 | 0.44 |
| ▸ | SLC28A2 | O43868 | 1/20 | 0.43 |
| ▸ | CDK1 | P06493 | 1/20 | 0.43 |
| ▸ | CCNB1 | P14635 | 1/20 | 0.43 |
| ▸ | CCNA2 | P20248 | 1/20 | 0.43 |
| ▸ | CDK2 | P24941 | 1/20 | 0.43 |
| ▸ | CCNA1 | P78396 | 1/20 | 0.43 |
| ▸ | SLC29A1 | Q99808 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19837987 | 1.00 | ADK (0.67) | ADKHSPA8HSPA5RXFP1CDK5 | |
| SCHEMBL19837990 | 0.87 | ADK (0.70) | ADKHSPA8HSPA5RXFP1CDK5 | |
| SCHEMBL19837996 | 0.86 | ADK (0.69) | ADKHSPA8HSPA5RXFP1CDK5 | |
| SCHEMBL19837963 | 0.86 | ADK (0.69) | ADKHSPA8HSPA5RXFP1CDK5 | |
| SCHEMBL21351720 | 0.84 | ADK (0.67) | ADKHSPA8HSPA5RXFP1CDK5 | |
| SCHEMBL19837981 | 0.84 | ADK (0.67) | ADKHSPA8HSPA5RXFP1CDK5 | |
| SCHEMBL19837970 | 0.84 | ADK (0.67) | ADKHSPA8HSPA5RXFP1CDK5 | |
| SCHEMBL19837972 | 0.81 | ADK (0.67) | ADKHSPA8HSPA5RXFP1CDK5 | |
| SCHEMBL21351704 | 0.80 | ADK (0.72) | ADK | |
| SCHEMBL21351701 | 0.80 | ADK (1.00) | ADKCCNA2CDK2CCNA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3494122-B1 | SUBSTITUTED HETEROPENTADIENO-PYRROLOPYRIMIDINE RIBONUCLEOSIDES FOR THERAPEUTIC USE | USTAV ORGANICKE CHEMIE A BIOCHEMIE AV CR V V I (CZ) | 2019-09-18 | — | — | EP | disclosed |