SCHEMBL2135207

SCHEMBL2135207

CC(C)=C[SiH2]O[Si](O[SiH2]C=C(C)C)(c1ccccc1)c1ccccc1

nearest known ligand 0.33

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
MAPT P10636 1/20 0.33
ESR1 P03372 1/20 0.31
ESR2 Q92731 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1679731 0.85 MAPT (0.33) MAPTESR1ESR2
SCHEMBL9419490 0.83 MAPT (0.32) MAPTESR1ESR2
SCHEMBL5701464 0.83 MAPT (0.32) MAPTESR1ESR2
SCHEMBL5377957 0.83 MAPT (0.35) MAPTESR1ESR2
SCHEMBL19469320 0.76
SCHEMBL2135202 0.73 MAPT (0.36) MAPTESR1ESR2
SCHEMBL10695074 0.70 ESR1 (0.33) ESR1ESR2
SCHEMBL27540698 0.69 CA4 (0.37)
SCHEMBL1092234 0.69 MAPT (0.35) MAPTESR1ESR2
SCHEMBL5701831 0.67 TP53 (0.39)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20140023929-A1 Silicon-Containing Carbonaceous Composite Material DOW CORNING TORAY CO., LTD. (JP) 2014-01-23 US disclosed
WO-2013115114-A1 SILICON-CONTAINING CARBON-BASED COMPOSITE MATERIAL DOW CORNING TORAY CO., LTD. (JP) 2013-08-08 WO disclosed
US-7863392-B2 Curable organopolysiloxane resin composition and optical part molded therefrom DOW CORNING TORAY COMPANY, LTD. (JP) 2011-01-04 US disclosed
EP-1699875-B1 ADDITION-CURABLE ORGANOPOLYSILOXANE RESIN COMPOSITION AND AN OPTICAL MATERIAL DOW CORNING TORAY CO LTD (JP) 2010-01-27 EP disclosed
US-7649059-B2 Addition-curable organopolysiloxane resin composition DOW CORNING TORAY COMPANY, LTD. (JP) 2010-01-19 US disclosed
US-7625986-B2 Additional-curable organopolysiloxane resin composition and an optical material DOW CORNING CORPORATION (US) 2009-12-01 US disclosed
EP-1695124-B1 ADDITION-CURABLE ORGANOPOLYSILOXANE RESIN COMPOSITION DOW CORNING TORAY CO LTD (JP) 2009-09-09 EP disclosed
US-20080033120-A1 Additional-Curable Organopolysiloxane Resin Composition and an Optical Material DOW TORAY CO., LTD. (JP) 2008-02-07 US disclosed
US-20070244214-A1 Addition-Curable Organopolysiloxane Resin Composition DOW CORNING TORAY COMPANY, LTD. (JP) 2007-10-18 US disclosed
EP-1699875-A2 ADDITION-CURABLE ORGANOPOLYSILOXANE RESIN COMPOSITION AND AN OPTICAL MATERIAL Dow Corning Toray Co., Ltd. (JP) 2006-09-13 EP disclosed
EP-1695124-A2 ADDITION-CURABLE ORGANOPOLYSILOXANE RESIN COMPOSITION Dow Corning Toray Co., Ltd. (JP) 2006-08-30 EP disclosed
WO-2005062080-A2 ADDITION-CURABLE ORGANOPOLYSILOXANE RESIN COMPOSITION DOW CORNING TORAY CO., LTD. (JP) 2005-07-07 WO disclosed
WO-2005054371-A2 ADDITION-CURABLE ORGANOPOLYSILOXANE RESIN COMPOSITION AND AN OPTICAL MATERIAL DOW CORNING TORAY CO., LTD. (JP) 2005-06-16 WO disclosed