SCHEMBL10695074

SCHEMBL10695074

C[SiH2]O[Si](O[SiH2]C)(c1ccccc1)c1ccccc1

nearest known ligand 0.33

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
ESR1 P03372 1/20 0.33
ESR2 Q92731 1/20 0.33
CA4 P22748 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21114725 0.85 ESR1 (0.32) ESR1ESR2
SCHEMBL11094517 0.85
SCHEMBL31277493 0.82 ESR1 (0.31) ESR1ESR2
SCHEMBL10784166 0.80 ESR1 (0.33) ESR1ESR2CA4
SCHEMBL3309054 0.80 ESR1 (0.33) ESR1ESR2CA4
SCHEMBL19484484 0.79
SCHEMBL250237 0.78 ESR1 (0.37) ESR1ESR2
SCHEMBL182248 0.78 ESR1 (0.37) ESR1ESR2
SCHEMBL11653537 0.76 ESR1 (0.31) ESR1ESR2
SCHEMBL6064639 0.76 ESR1 (0.35) ESR1ESR2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4737563-A USING DIHYDROISOPROPENYLOXYSILANE SHIN-ETSU CHEMICAL CO., LTD. (JP) 1988-04-12 US disclosed