SCHEMBL1679731

SCHEMBL1679731

CC(C)=C[SiH2]O[Si](O[SiH2]C=C(C)C)(O[SiH2]C=C(C)C)c1ccccc1

nearest known ligand 0.33

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
MAPT P10636 1/20 0.33
ESR1 P03372 1/20 0.31
ESR2 Q92731 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19469320 0.87
SCHEMBL2135207 0.85 MAPT (0.33) MAPTESR1ESR2
SCHEMBL5377957 0.83 MAPT (0.35) MAPTESR1ESR2
SCHEMBL9419490 0.83 MAPT (0.32) MAPTESR1ESR2
SCHEMBL5701464 0.83 MAPT (0.32) MAPTESR1ESR2
SCHEMBL5701525 0.79 ALDH1A1 (0.37)
SCHEMBL5701831 0.77 TP53 (0.39)
SCHEMBL1679728 0.73 MAPT (0.36) MAPTESR1ESR2
SCHEMBL5701394 0.73 ALDH1A1 (0.32)
SCHEMBL3309054 0.70 ESR1 (0.33) ESR1ESR2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 96 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9045667-B2 Curable silicone composition, cured product thereof, and optical semiconductor device DOW CORNING TORAY CO., LTD. (JP) 2015-06-02 US claimed
US-20140377570-A1 Curable Silicone Composition, Cured Product Thereof, And Optical Semiconductor Device DOW CORNING TORAY CO., LTD. (JP) 2014-12-25 US claimed
EP-1235877-B1 THERMOPLASTIC SILICONE ELASTOMERS BASED ON FLUOROCARBON RESIN DOW CORNING (US) 2005-03-23 EP claimed
EP-1235877-A1 THERMOPLASTIC SILICONE ELASTOMERS BASED ON FLUOROCARBON RESIN DOW CORNING CORPORATION (US) 2002-09-04 EP claimed
WO-2001019914-A1 THERMOPLASTIC SILICONE ELASTOMERS BASED ON FLUOROCARBON RESIN DOW CORNING CORPORATION (US) 2001-03-22 WO claimed
US-6015858-A CURING; TENSILE STRENGTH, ELONGATION DOW CORNING CORPORATION (US) 2000-01-18 US claimed
WO-2025074949-A1 ULTRAVIOLET-CURABLE COMPOSITION ダウ・東レ株式会社 2025-04-10 WO disclosed
WO-2025074950-A1 THERMOSETTING COMPOSITION ダウ・東レ株式会社 2025-04-10 WO disclosed
WO-2024241960-A1 THERMOSETTING COMPOSITION, PREPREG INCLUDING SAME, AND HIGH-FREQUENCY CIRCUIT BOARD ダウ・東レ株式会社 2024-11-28 WO disclosed
CN-115279835-A Photocurable liquid silicone composition, cured product thereof, optical filler comprising same, and display device comprising layer formed from cured product 陶氏东丽株式会社 2022-11-01 CN disclosed
US-10351675-B2 Compositions and methods for injectable composition for an accommodating instraocular lens ADVENTUS TECHNOLOGY, INC. (US) 2019-07-16 US disclosed
US-20180273687-A1 Compositions and Methods for Injectable Composition for an Accommodating Instraocular Lens ADVENTUS TECHNOLOGY, INC. 2018-09-27 US disclosed
EP-2772505-B1 PHOTOCURABLE RESIN COMPOSITION AND NOVEL SILOXANE COMPOUND ADEKA CORP (JP) 2017-11-15 EP disclosed
EP-1481979-A1 Preparation of branched tetrasiloxane SHIN-ETSU CHEMICAL CO., LTD. (JP) 2004-12-01 EP disclosed
WO-2004090041-A2 CURABLE ORGANOPOLYSILOXANE RESIN COMPOSITION FOR OPTICAL TRANSMISSION COMPONENTS, OPTICAL TRANSMISSION COMPONENTS, AND FABRICATION PROCESS THEREOF DOW CORNING ASIA LTD. (JP) 2004-10-21 WO disclosed
WO-2003104322-A1 FLUOROCARBON ELASTOMER SILICONE VULCANIZATES DOW CORNING CORPORATION (US) 2003-12-18 WO disclosed
WO-2003104323-A1 FLUOROCARBON ELASTOMER SILICONE VULCANIZATES DOW CORNING CORPORATION (US) 2003-12-18 WO disclosed
EP-1235877-A1 THERMOPLASTIC SILICONE ELASTOMERS BASED ON FLUOROCARBON RESIN DOW CORNING CORPORATION (US) 2002-09-04 EP disclosed
WO-2001019914-A1 THERMOPLASTIC SILICONE ELASTOMERS BASED ON FLUOROCARBON RESIN DOW CORNING CORPORATION (US) 2001-03-22 WO disclosed
US-6015858-A CURING; TENSILE STRENGTH, ELONGATION DOW CORNING CORPORATION (US) 2000-01-18 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10351675-B2 Compositions and methods for injectable composition for an accommodating instraocular lens MCM6, INCENP, PSMA6 MAPT 2554/4885ESR1 2425/4885ESR2 4554/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.