SCHEMBL2135683

SCHEMBL2135683

C=COC(C)N1C(=O)NC(C)(C)C1=O

nearest known ligand 0.36

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
POLB P06746 1/20 0.36
KMT2A Q03164 3/20 0.33
TSHR P16473 3/20 0.33
MEN1 O00255 2/20 0.33
LMNA P02545 1/20 0.33
L3MBTL1 Q9Y468 1/20 0.32
GAA P10253 1/20 0.31
HSD17B10 Q99714 1/20 0.31
SMN1; SMN2 Q16637 1/20 0.31
ALDH1A1 P00352 1/20 0.31
MAPK1 P28482 1/20 0.31
AR P10275 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11394834 0.80 POLB (0.47) POLBKMT2AMEN1LMNAL3MBTL1
SCHEMBL12042277 0.73 POLB (0.46) POLBKMT2ATSHRMEN1LMNA
SCHEMBL11393081 0.70
SCHEMBL11384762 0.70 POLB (0.43) POLBKMT2ATSHRMEN1LMNA
SCHEMBL21169208 0.70 POLB (0.43) POLBKMT2ATSHRMEN1LMNA
SCHEMBL1513862 0.68 POLB (0.42) POLBKMT2ATSHRMEN1LMNA
SCHEMBL9668855 0.68 MGLL (0.32)
SCHEMBL1159787 0.67 POLB (0.45) POLBKMT2ATSHRMEN1LMNA
SCHEMBL13745559 0.67 POLB (0.45) POLBKMT2ATSHRMEN1LMNA
SCHEMBL11384347 0.67

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20150191607-A1 Anti-fouling Paints and Coatings REACTIVE SURFACES, LTD (US) 2015-07-09 US disclosed
US-20140196631-A1 VISUAL ASSAYS FOR COATINGS INCORPORATING BIOACTIVE ENZYMES FOR CATALYTIC FUNCTIONS REACTIVE SURFACE, LTD. (US) 2014-07-17 US disclosed
US-20120097194-A1 Polymeric Coatings Incorporating Bioactive Enzymes for Catalytic Function REACTIVE SURFACES, LTD. (US) 2012-04-26 US disclosed
US-20110250626-A1 Visual Assays for Coatings Incorporating Bioactive Enzymes for Catalytic Functions REACTIVE SURFACES, LTD. (US) 2011-10-13 US disclosed
US-20110240064-A1 Polymeric Coatings Incorporating Bioactive Enzymes for Cleaning a Surface REACTIVE SURFACES, LTD. (US) 2011-10-06 US disclosed
US-20100210745-A1 Molecular Healing of Polymeric Materials, Coatings, Plastics, Elastomers, Composites, Laminates, Adhesives, and Sealants by Active Enzymes REACTIVE SURFACES, LTD. (US) 2010-08-19 US disclosed
EP-0113315-B1 FIBRE PREPREGS COATED WITH TWO DIFFERENT RESINS CIBA-GEIGY AG (CH) 1987-09-30 EP disclosed
US-4486494-A CONSTRUCTION MATERIALS CIBA-GEIGY CORPORATION (US) 1984-12-04 US disclosed
EP-0113315-A2 Fibre prepregs coated with two different resins CIBA-GEIGY AG (CH) 1984-07-11 EP disclosed
US-4386192-A BY SPECIFIC RATIOS OF TOLUENE AND CYCLOHEXANE POLYMERIZATION SOLVENTS CIBA-GEIGY CORPORATION (US) 1983-05-31 US disclosed
US-4256867-A OF HYDANTOIN, USED AS THICKENERS, SOLUBILIZERS, STABILIZERS, COMPLEXING AGENTS CIBA-GEIGY CORPORATION (US) 1981-03-17 US disclosed
US-4206309-A HYDANTOINALKYL VINYL ETHER CIBA-GEIGY CORPORATION (US) 1980-06-03 US disclosed