Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NT5E | P21589 | 1/20 | 0.44 |
| ▸ | P2RY12 | Q9H244 | 1/20 | 0.44 |
| ▸ | PRMT6 | Q96LA8 | 1/20 | 0.44 |
| ▸ | BMPR1B | O00238 | 1/20 | 0.43 |
| ▸ | ADORA1 | P30542 | 2/20 | 0.43 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.42 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.42 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8619444 | 0.92 | SLC29A1 (0.47) | ADORA1ADORA3ADORA2AADORA2B | |
| SCHEMBL8619439 | 0.92 | SLC29A1 (0.47) | ADORA1ADORA3ADORA2AADORA2B | |
| SCHEMBL19146419 | 0.89 | PRMT6 (0.44) | P2RY12PRMT6BMPR1BADORA1ADORA3 | |
| SCHEMBL18496467 | 0.81 | SLC29A1 (0.59) | ADORA1ADORA3ADORA2AADORA2B | |
| SCHEMBL31160198 | 0.81 | SLC29A1 (0.59) | ADORA1ADORA3ADORA2AADORA2B | |
| SCHEMBL18496429 | 0.79 | SLC29A1 (0.48) | P2RY12PRMT6ADORA1ADORA3ADORA2A | |
| SCHEMBL23881920 | 0.79 | SLC29A1 (0.49) | P2RY12ADORA3 | |
| SCHEMBL21539900 | 0.79 | ADORA1 (0.46) | P2RY12PRMT6ADORA1ADORA3ADORA2A | |
| SCHEMBL18496420 | 0.78 | P2RY12 (0.45) | P2RY12PRMT6ADORA1ADORA3ADORA2A | |
| SCHEMBL7247160 | 0.78 | BMPR1B (0.53) | P2RY12PRMT6BMPR1BADORA1ADORA3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3765474-B1 | CYCLOPENTANE-BASED MODULATORS OF STING (STIMULATOR OF INTERFERON GENES) | PFIZER (US) | 2022-06-15 | — | — | EP | disclosed |
| EP-3765474-A1 | CYCLOPENTANE-BASED MODULATORS OF STING (STIMULATOR OF INTERFERON GENES) | Pfizer Inc (US) | 2021-01-20 | — | — | EP | disclosed |
| WO-2019175776-A1 | CYCLOPENTANE-BASED MODULATORS OF STING (STIMULATOR OF INTERFERON GENES) | PFIZER INC. (US) | 2019-09-19 | — | — | WO | disclosed |