Known targets — ChEMBL curated mechanism
ACHEBDKRB2CHRM1CHRM2CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNGGUCY1A1GUCY1A2GUCY1B1GUCY1B2NAMPTPTAFRSLC10A2SLC6A2SLC6A3TACR1dacAdacBdacCftsImrcAmrcBmrdA
The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Fluoride Ion SCHEMBL3470298 | 0.98 | — | — | |
| Hydrochloric Acid SCHEMBL3663761 | 0.80 | — | — | |
| Hydrochloric Acid SCHEMBL3693756 | 0.80 | — | — | |
| Hydrochloric Acid SCHEMBL8160665 | 0.79 | HTR6 (0.31) | — | |
| SCHEMBL9280864 | 0.79 | — | — | |
| SCHEMBL3806740 | 0.78 | — | — | |
| SCHEMBL2134687 | 0.78 | — | — | |
| Hydrochloric Acid SCHEMBL8159968 | 0.76 | CHRM2 (0.30) | — | |
| Hydrochloric Acid SCHEMBL3894869 | 0.76 | — | — | |
| SCHEMBL2868966 | 0.74 | MEN1 (0.33) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8524627-B2 | Activating supports with controlled distribution of OH groups | TOTAL RESEARCH & TECHNOLOGY FELUY (BE) | 2013-09-03 | — | — | US | disclosed |
| EP-2328939-B1 | ACTIVATING SUPPORTS BASED ON PERFLUORINATED BORONIC ACIDS | TOTAL RES & TECHNOLOGY FELUY (BE) | 2012-12-12 | — | — | EP | disclosed |
| US-20120101239-A1 | ACTIVATING SUPPORTS WITH CONTROLLED DISTRIBUTION OF OH GROUPS | CENTRE NATIONAL DE LA RESCHERCHE SCIENTIFIQUE (FR) | 2012-04-26 | — | — | US | disclosed |
| EP-2251362-A1 | Activating supports with controlled distribution of OH groups | TOTAL PETROCHEMICALS RESEARCH FELUY (BE) | 2010-11-17 | — | — | EP | disclosed |
| US-7759271-B2 | Activating supports for metallocene catalysis | TOTAL PETROCHEMICALS RESEARCH FELUY (BE) | 2010-07-20 | — | — | US | disclosed |
| EP-2172493-A1 | Activating supports based on perfluorinated boronic acids | TOTAL PETROCHEMICALS RESEARCH FELUY (BE) | 2010-04-07 | — | — | EP | disclosed |
| US-20090042720-A1 | Activating supports for metallocene catalysis | TOTAL PETROCHEMICALS RESEARCH FELUY (BE) | 2009-02-12 | — | — | US | disclosed |
| EP-1709091-A2 | ACTIVATING SUPPORTS FOR METALLOCENE CATALYSIS | TOTAL PETROCHEMICALS RESEARCH FELUY (BE) | 2006-10-11 | — | — | EP | disclosed |
| WO-2005075525-A2 | ACTIVATING SUPPORTS FOR METALLOCENE CATALYSIS. | TOTAL PETROCHEMICALS RESEARCH FELUY (BE) | 2005-08-18 | — | — | WO | disclosed |
| EP-1559730-A1 | Activating supports for metallocene catalysis | TOTAL PETROCHEMICALS RESEARCH FELUY (BE) | 2005-08-03 | — | — | EP | disclosed |