Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 4/20 | 0.66 |
| ▸ | MEN1 | O00255 | 3/20 | 0.66 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.65 |
| ▸ | LMNA | P02545 | 2/20 | 0.65 |
| ▸ | CASP3 | P42574 | 1/20 | 0.64 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.64 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.64 |
| ▸ | GAA | P10253 | 1/20 | 0.64 |
| ▸ | GSK3B | P49841 | 1/20 | 0.63 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.62 |
| ▸ | RAB9A | P51151 | 1/20 | 0.62 |
| ▸ | F3 | P13726 | 2/20 | 0.62 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.60 |
| ▸ | THRB | P10828 | 1/20 | 0.60 |
| ▸ | ATM | Q13315 | 1/20 | 0.60 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.58 |
| ▸ | MAPT | P10636 | 1/20 | 0.57 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.57 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.57 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.57 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2135879 | 1.00 | KMT2A (0.66) | KMT2AMEN1TDP1LMNACASP3 | |
| SCHEMBL2139839 | 0.92 | KMT2A (0.61) | KMT2AMEN1TDP1LMNACASP3 | |
| SCHEMBL2139845 | 0.92 | KMT2A (0.61) | KMT2AMEN1TDP1LMNACASP3 | |
| SCHEMBL14274008 | 0.92 | KMT2A (0.57) | KMT2AMEN1TDP1LMNACASP3 | |
| SCHEMBL27547880 | 0.88 | GAA (0.64) | KMT2AMEN1TDP1LMNACASP3 | |
| SCHEMBL27547878 | 0.88 | GAA (0.64) | KMT2AMEN1TDP1LMNACASP3 | |
| SCHEMBL9855976 | 0.87 | LMNA (0.68) | KMT2AMEN1TDP1LMNACASP3 | |
| SCHEMBL9855983 | 0.87 | LMNA (0.68) | KMT2AMEN1TDP1LMNACASP3 | |
| SCHEMBL10784966 | 0.86 | KMT2A (0.61) | KMT2AMEN1TDP1LMNACASP3 | |
| SCHEMBL10784973 | 0.86 | KMT2A (0.61) | KMT2AMEN1TDP1LMNACASP3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7863478-B2 | 1,3-Bis-[3-(4-methoxyphenyl)-2-propenoyloxy]-2-oxopropane; novel alpha-hydroxyketone derivatives as light-protection filters for cosmetic or drug products; used in cosmetic protective coatings; solar radiation; sunscreen agents; aging resistance; wrinkle resistance; food additives; dermatology | MERCK PATENT GMBH (DE) | 2011-01-04 | — | — | US | disclosed |
| US-20080038213-A1 | Uv Filters | MERCK PATENT GMBH (DE) | 2008-02-14 | — | — | US | disclosed |
| EP-1776351-A1 | UV FILTER | MERCK PATENT GmbH (DE) | 2007-04-25 | — | — | EP | disclosed |
| WO-2006018104-A1 | UV FILTER | MERCK PATENT GMBH (DE) | 2006-02-23 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080038213-A1 | Uv Filters | ERCC4, ERCC1, ERCC5 | KMT2A 3367/4885MEN1 571/4885TDP1 1260/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.