Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EED | O75530 | 4/20 | 0.49 |
| ▸ | HRH3 | Q9Y5N1 | 3/20 | 0.48 |
| ▸ | HRH4 | Q9H3N8 | 2/20 | 0.48 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.46 |
| ▸ | CHKA | P35790 | 1/20 | 0.38 |
| ▸ | PDE9A | O76083 | 1/20 | 0.37 |
| ▸ | BRD4 | O60885 | 1/20 | 0.37 |
| ▸ | ATAD2 | Q6PL18 | 1/20 | 0.37 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.37 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.37 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.37 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.37 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.37 |
| ▸ | KDM1A | O60341 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30962118 | 1.00 | EED (0.49) | EEDHRH3HRH4KCNH2CHKA | |
| SCHEMBL21358974 | 1.00 | EED (0.49) | EEDHRH3HRH4KCNH2CHKA | |
| SCHEMBL20281864 | 0.91 | HRH4 (0.45) | EEDHRH3HRH4KCNH2CHKA | |
| SCHEMBL2990172 | 0.84 | CHRNB2 (0.39) | CHKAPDE9ACHRNB2CHRNA4 | |
| SCHEMBL25819753 | 0.82 | PDE9A (0.39) | HRH3KCNH2PDE9ACHRNB2CHRNA4 | |
| SCHEMBL12255484 | 0.81 | GBA1 (0.51) | HRH3HRH4KCNH2PDE9AKDM1A | |
| SCHEMBL21241330 | 0.81 | PDE9A (0.41) | HRH3HRH4KCNH2PDE9ACHRNB2 | |
| SCHEMBL14609341 | 0.80 | EED (0.55) | EEDHRH3HRH4KCNH2KDM1A | |
| SCHEMBL12147777 | 0.79 | PDE10A (0.40) | PDE9ACHRNB2CHRNA4 | |
| SCHEMBL21358981 | 0.78 | EED (0.54) | EEDHRH3HRH4KCNH2CHKA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112218863-B | O-glycoprotein-2-acetamido-2-deoxy-3-D-pyranoside enzyme inhibitors | 比奥根MA公司 | 2024-07-12 | — | — | CN | disclosed |
| EP-4186899-A1 | O-GLYCOPROTEIN-2-ACETAMIDO-2-DEOXY-3-D-GLYCOPYRANOSIDASE INHIBITORS | Biogen MA Inc. (US) | 2023-05-31 | — | — | EP | disclosed |
| US-20230117898-A1 | O-GLYCOPROTEIN-2-ACETAMIDO-2-DEOXY-3-D-GLYCOPYRANOSIDASE INHIBITORS | BIOGEN MA INC. | 2023-04-20 | — | — | US | disclosed |
| EP-3765458-B1 | O-GLYCOPROTEIN-2-ACETAMIDO-2-DEOXY-3-D-GLYCOPYRANOSIDASE INHIBITORS | BIOGEN MA INC (US) | 2023-01-11 | — | — | EP | disclosed |
| US-11459324-B2 | O-glycoprotein-2-acetamido-2-deoxy-3-D-glycopyranosidase inhibitors | BIOGEN MA INC. (US) | 2022-10-04 | — | — | US | disclosed |
| US-20210040080-A1 | O-GLYCOPROTEIN-2-ACETAMIDO-2-DEOXY-3-D-GLYCOPYRANOSIDASE INHIBITORS | BIOGEN MA INC. | 2021-02-11 | — | — | US | disclosed |
| EP-3765458-A1 | O-GLYCOPROTEIN-2-ACETAMIDO-2-DEOXY-3-D-GLYCOPYRANOSIDASE INHIBITORS | Biogen MA Inc. (US) | 2021-01-20 | — | — | EP | disclosed |
| CN-112218863-A | O-glycoprotein-2-acetamido-2-deoxy-3-D-pyranosidase inhibitors | 比奥根MA公司 | 2021-01-12 | — | — | CN | disclosed |
| WO-2019178191-A1 | O-GLYCOPROTEIN-2-ACETAMIDO-2-DEOXY-3-D-GLYCOPYRANOSIDASE INHIBITORS | BIOGEN MA INC. (US) | 2019-09-19 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230117898-A1 | O-GLYCOPROTEIN-2-ACETAMIDO-2-DEOXY-3-D-GLYCOPYRANOSIDASE INHIBITORS | MGAT3, ST3GAL3, ST6GAL1 | EED 4747/4885HRH3 3419/4885HRH4 3222/4885 |
| US-11459324-B2 | O-glycoprotein-2-acetamido-2-deoxy-3-D-glycopyranosidase inhibitors | MGAT3, ST6GAL1, ST3GAL3 | EED 4788/4885HRH3 3081/4885HRH4 2920/4885 |
| US-20210040080-A1 | O-GLYCOPROTEIN-2-ACETAMIDO-2-DEOXY-3-D-GLYCOPYRANOSIDASE INHIBITORS | MGAT3, ST6GAL1, ST3GAL3 | EED 4788/4885HRH3 3081/4885HRH4 2920/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.