SCHEMBL21359751

SCHEMBL21359751

CCCc1ccc(O)c(C)c1.Cc1cccc(C)c1O

nearest known ligand 0.55

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CNR1 P21554 1/20 0.55
CNR2 P34972 1/20 0.55
ESR1 P03372 7/20 0.53
ESR2 Q92731 5/20 0.53
ALDH1A1 P00352 3/20 0.48
ALOX5 P09917 1/20 0.44
TRPA1 O75762 1/20 0.44
GAA P10253 2/20 0.43
MAPT P10636 2/20 0.43
KDM4E B2RXH2 1/20 0.43
PSMD14 O00487 1/20 0.43
USP2 O75604 1/20 0.43
POLB P06746 1/20 0.43
ALOX12 P18054 1/20 0.43
HTT P42858 1/20 0.43
HSD17B10 Q99714 1/20 0.43
AR P10275 2/20 0.43
PTGS1 P23219 1/20 0.42
PTGS2 P35354 1/20 0.42
PKM P14618 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL332894 0.89 CNR1 (0.67) CNR1CNR2ESR1ESR2ALOX5
SCHEMBL21357973 0.85 CNR1 (0.53) CNR1CNR2ESR1ESR2ALOX5
Phenol SCHEMBL8323704 0.83 CNR1 (0.55) CNR1CNR2ESR1ESR2ALOX5
SCHEMBL7652458 0.80 ALDH1A1 (0.54) CNR1CNR2ESR1ESR2ALDH1A1
SCHEMBL1924746 0.79 ESR1 (0.74) CNR1CNR2ESR1ESR2ALDH1A1
SCHEMBL29720481 0.79 ESR1 (0.74) CNR1CNR2ESR1ESR2ALDH1A1
SCHEMBL2475751 0.78 NPC1 (0.62) CNR1CNR2ESR1ESR2HTT
SCHEMBL922815 0.77 ESR1 (0.66) ESR1ESR2ALDH1A1TRPA1GAA
SCHEMBL10388452 0.77 ESR1 (0.59) ESR1ESR2
SCHEMBL28683951 0.77 NPC1 (0.60) CNR1CNR2ESR1ESR2HTT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2019176855-A1 METHOD FOR PRODUCING POLY(VINYLBENZYL)ETHER COMPOUND 第一工業製薬株式会社 2019-09-19 WO disclosed