SCHEMBL29720481

SCHEMBL29720481

Cc1cc(CCc2ccc(O)c(C)c2)ccc1O

nearest known ligand 0.74

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ESR1 P03372 5/20 0.74
ESR2 Q92731 4/20 0.74
TP53 P04637 2/20 0.54
TDP1 Q9NUW8 1/20 0.54
ALOX15 P16050 3/20 0.50
AR P10275 3/20 0.50
IGF1R P08069 2/20 0.50
CNR1 P21554 1/20 0.50
CNR2 P34972 1/20 0.50
PTGS1 P23219 1/20 0.50
PTGS2 P35354 1/20 0.50
PDE10A Q9Y233 1/20 0.50
MAPT P10636 2/20 0.48
KDM4E B2RXH2 1/20 0.48
ALDH1A1 P00352 1/20 0.48
ALOX5 P09917 1/20 0.48
GAA P10253 1/20 0.48
BACE1 P56817 1/20 0.48
AKR1B1 P15121 1/20 0.47
CYP1A2 P05177 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1924746 1.00 ESR1 (0.74) ESR1ESR2TP53TDP1ALOX15
SCHEMBL3241376 0.91 ESR1 (0.63) ESR1ESR2TP53TDP1ALOX15
SCHEMBL529618 0.91 ESR1 (0.68) ESR1ESR2TP53TDP1ALOX15
SCHEMBL68664 0.91 ESR1 (0.68) ESR1ESR2TP53TDP1ALOX15
SCHEMBL172708 0.89 ESR1 (0.61) ESR1ESR2TP53TDP1ALOX15
SCHEMBL8402779 0.89 ESR1 (0.65) ESR1ESR2TP53TDP1ALOX15
SCHEMBL16065724 0.89 ESR1 (0.65) ESR1ESR2TP53TDP1ALOX15
SCHEMBL6227927 0.89 ESR1 (0.65) ESR1ESR2TP53TDP1ALOX15
SCHEMBL12949979 0.89 ESR1 (0.65) ESR1ESR2TP53TDP1ALOX15
SCHEMBL332894 0.89 CNR1 (0.67) ESR1ESR2TP53TDP1AR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-115698131-B Curable thermoset compositions comprising poly (arylene ether) copolymers 高新特殊工程塑料全球技术有限公司 2025-06-17 CN disclosed
CN-111004385-B Poly (arylene ether) copolymer 高新特殊工程塑料全球技术有限公司 2024-04-12 CN disclosed
CN-117659387-A Poly (arylene ether) copolymer 高新特殊工程塑料全球技术有限公司 2024-03-08 CN disclosed
CN-117255812-A Blocked bisphenol polydiindane oligomers and compositions, methods of manufacture, and articles made therefrom 高新特殊工程塑料全球技术有限公司 2023-12-19 CN disclosed
CN-117178007-A Phenylether oligomers and curable thermoset compositions comprising the same 高新特殊工程塑料全球技术有限公司 2023-12-05 CN disclosed
CN-114616263-A Curing composition for toughening epoxy resins 高新特殊工程塑料全球技术有限公司 2022-06-10 CN disclosed