SCHEMBL21360003

SCHEMBL21360003

Oc1ccc(C2C=CCC=C2)cc1

nearest known ligand 0.40

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ESR2 Q92731 13/20 0.40
CYP3A4 P08684 2/20 0.38
ALOX15 P16050 2/20 0.38
KDM4E B2RXH2 1/20 0.38
MEN1 O00255 1/20 0.38
NPC1 O15118 1/20 0.38
CA12 O43570 1/20 0.38
GMNN O75496 1/20 0.38
ALDH1A1 P00352 1/20 0.38
CA1 P00915 1/20 0.38
CA2 P00918 1/20 0.38
LMNA P02545 1/20 0.38
CA3 P07451 1/20 0.38
MAPT P10636 1/20 0.38
TYR P14679 1/20 0.38
HPGD P15428 1/20 0.38
NFKB1 P19838 1/20 0.38
CA4 P22748 1/20 0.38
CA5A P35218 1/20 0.38
THPO P40225 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2719092 0.82 MEN1 (0.50) ESR2CYP3A4ALOX15KDM4EMEN1
SCHEMBL15095470 0.82 MEN1 (0.50) ESR2CYP3A4ALOX15KDM4EMEN1
SCHEMBL4349198 0.76 MAPT (0.39) CYP3A4ALOX15MEN1ALDH1A1CA1
SCHEMBL3740188 0.75 RECQL (0.39) CYP3A4LMNARECQLBLMPMP22
SCHEMBL21358187 0.74 CA12 (0.42) CYP3A4CA12ALDH1A1CA2LMNA
SCHEMBL21755365 0.74 ESR2 (0.35) ESR2CYP3A4ALOX15KDM4EMEN1
SCHEMBL3676245 0.70 DYRK1A (0.38) ESR2ALOX15CA12ALDH1A1CA1
Hydroquinone SCHEMBL28773334 0.68 MAPT (0.53) ESR2CYP3A4ALOX15KDM4EMEN1
SCHEMBL8287019 0.67 ESR2 (0.36) ESR2CYP3A4ALOX15KDM4EMEN1
SCHEMBL18726005 0.65 ESR2 (0.54) ESR2CYP3A4ALOX15KDM4EMEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2019177117-A1 DRUG FOR TREATING COUGH 日本ケミファ株式会社 2019-09-19 WO claimed
CN-118339201-A Vinyl compound, method for producing vinyl compound, vinyl composition, vinyl resin cured product, prepreg, resin-coated film, resin-coated metal foil, metal-clad laminate, and printed wiring board 住友化学株式会社 2024-07-12 CN disclosed
WO-2019177117-A1 DRUG FOR TREATING COUGH 日本ケミファ株式会社 2019-09-19 WO disclosed
CN-103237794-A P2X4Receptor antagonists NIPPONCHEMIPHAR CO LTD 2013-08-07 CN disclosed