Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DYRK1A | Q13627 | 1/20 | 0.38 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.35 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.35 |
| ▸ | HTR2A | P28223 | 5/20 | 0.34 |
| ▸ | HTR2C | P28335 | 5/20 | 0.34 |
| ▸ | HTR2B | P41595 | 1/20 | 0.34 |
| ▸ | CA2 | P00918 | 2/20 | 0.32 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.32 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.32 |
| ▸ | MIF | P14174 | 1/20 | 0.32 |
| ▸ | TYR | P14679 | 1/20 | 0.32 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
| ▸ | MAOB | P27338 | 1/20 | 0.32 |
| ▸ | CA12 | O43570 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11159023 | 0.74 | DYRK1A (0.36) | DYRK1ACHRNB2CHRNA4CA2PTGS2 | |
| SCHEMBL21360003 | 0.70 | ESR2 (0.40) | CA2ALDH1A1LMNACYP2C9TYR | |
| SCHEMBL14283801 | 0.69 | ESR1 (0.36) | DYRK1ACHRNB2CHRNA4HTR2AHTR2C | |
| SCHEMBL21358187 | 0.68 | CA12 (0.42) | HTR2AHTR2CHTR2BCA2ALDH1A1 | |
| SCHEMBL7929735 | 0.67 | DYRK1A (0.40) | DYRK1ACHRNB2CHRNA4CA2PTGS2 | |
| SCHEMBL10899805 | 0.67 | NUDT1 (0.54) | DYRK1ACHRNB2CHRNA4ALDH1A1CYP2C9 | |
| SCHEMBL69755 | 0.65 | NUDT1 (0.57) | DYRK1ACHRNB2CHRNA4ALDH1A1CYP2C9 | |
| SCHEMBL9640917 | 0.63 | ESR2 (0.55) | DYRK1ACHRNB2CHRNA4NR1I2ALDH1A1 | |
| SCHEMBL8313932 | 0.63 | QDPR (0.55) | CHRNB2CHRNA4HTR2CCYP2C9ESR1 | |
| SCHEMBL16046506 | 0.63 | CHRNB2 (0.38) | DYRK1ACHRNB2CHRNA4PTGS2NR1I2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100036056-A1 | RADICAL COLD CURING OF SYNTHETIC RESINS BASED ON MODIFIED POLY(METH) ACRYLATES COMPRISING REACTIVE ETHYLENIC GROUPS | ASHLAND-SÜDCHEMIE KERNFEST GMBH (DE) | 2010-02-11 | — | — | US | disclosed |