Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RECQL | P46063 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | MAOB | P27338 | 8/20 | 0.37 |
| ▸ | MAOA | P21397 | 7/20 | 0.37 |
| ▸ | KDM1A | O60341 | 5/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 5/20 | 0.37 |
| ▸ | CYP2B6 | P20813 | 3/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.37 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.37 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.37 |
| ▸ | ADRA1A | P35348 | 2/20 | 0.37 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.37 |
| ▸ | LMNA | P02545 | 2/20 | 0.37 |
| ▸ | TAAR1 | Q96RJ0 | 2/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | HTR1A | P08908 | 1/20 | 0.37 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.37 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.37 |
| ▸ | HTR2C | P28335 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4356377 | 0.80 | RECQL (0.42) | RECQLTSHRMAOBMAOAKDM1A | |
| SCHEMBL10557917 | 0.75 | CYP1A2 (0.42) | RECQLTSHRCYP2C19CYP1A2CYP2D6 | |
| SCHEMBL21360003 | 0.75 | ESR2 (0.40) | RECQLKDM1ACYP2C9LMNACYP3A4 | |
| SCHEMBL4349198 | 0.75 | MAPT (0.39) | KDM1ACYP2C19CYP1A2CYP2C9CYP3A4 | |
| SCHEMBL7774927 | 0.75 | RECQL (0.39) | RECQLTSHRMAOBMAOAKDM1A | |
| SCHEMBL21358187 | 0.73 | CA12 (0.42) | LMNACYP3A4HTR2CDRD3HSD17B10 | |
| SCHEMBL21358312 | 0.73 | HTR2A (0.42) | MAOBMAOAKDM1ASLC6A2SLC6A3 | |
| SCHEMBL21360103 | 0.73 | CYP3A4 (0.42) | RECQLTSHRMAOBMAOALMNA | |
| SCHEMBL11320221 | 0.72 | RECQL (0.37) | RECQLTSHRMAOBMAOAKDM1A | |
| Methylamine SCHEMBL4256041 | 0.72 | CYP1A2 (0.44) | RECQLMAOBMAOAKDM1ACYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 19 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-60190756-A | — | — | None | — | — | JP | disclosed |
| US-9689025-B2 | Nucleic acid element for use in analysis, and analytical method, analytical reagent, and analytical instrument using same | NEC SOLUTION INNOVATORS, LTD. (JP) | 2017-06-27 | — | — | US | disclosed |
| EP-2772761-A2 | Nucleic acid element for use in analysis, and analytical method, analytical reagent and analytical instrument using same | NEC Soft, Ltd. (JP) | 2014-09-03 | — | — | EP | disclosed |
| US-8487071-B2 | Polyether polymer and production process thereof | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2013-07-16 | — | — | US | disclosed |
| US-20120202195-A1 | NUCLEIC ACID ELEMENT FOR USE IN ANALYSIS, AND ANALYTICAL METHOD, ANALYTICAL REAGENT, AND ANALYTICAL INSTRUMENT USING SAME | NEC SOFT, LTD. (JP) | 2012-08-09 | — | — | US | disclosed |
| EP-2463660-A1 | NUCLEIC ACID ELEMENT FOR USE IN ANALYSIS, AND ANALYTICAL METHOD, ANALYTICAL REAGENT AND ANALYTICAL INSTRUMENT USING SAME | NEC Soft, Ltd. (JP) | 2012-06-13 | — | — | EP | disclosed |
| US-20110065889-A1 | POLYETHER POLYMER AND PRODUCTION PROCESS THEREOF | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2011-03-17 | — | — | US | disclosed |
| US-20100291236-A1 | OSMIUM COMPOUNDS | THE UNIVERSITY OF WARWICK (GB) | 2010-11-18 | — | — | US | disclosed |
| WO-2009142094-A1 | POLYETHER POLYMER AND PRODUCTION PROCESS THEREOF | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2009-11-26 | — | — | WO | disclosed |
| EP-2054425-A1 | OSMIUM COMPOUNDS | The University Of Warwick (GB) | 2009-05-06 | — | — | EP | disclosed |
| WO-2008017855-A1 | OSMIUM COMPOUNDS | THE UNIVERSITY OF WARWICK (GB) | 2008-02-14 | — | — | WO | disclosed |
| US-6979681-B2 | Half-sandwich ruthenium (II) compounds comprising nitrogen containing ligands for treatment of cancer | UNIVERSITY COURT, THE UNIVERSITY OF EDINBURGH (GB) | 2005-12-27 | — | — | US | disclosed |
| US-20050239765-A1 | Half-sandwich ruthenium (II) compounds comprising nitrogen containing ligands for treatment of cancer | UNIVERSITY COURT, THE UNIVERSITY OF EDINBURGH, A UNITED KINGDOM CORPORATION | 2005-10-27 | — | — | US | disclosed |
| EP-1224192-B1 | HALF-SANDWICH RUTHENIUM (II) COMPOUNDS COMPRISING NITROGEN CONTAINING LIGANDS FOR TREATMENT OF CANCER | UNIV COURT THE UNIVERSITY OF E (GB) | 2005-08-31 | — | — | EP | disclosed |
| US-20040220166-A1 | Half-sandwich ruthenium (II) compounds comprising nitrogen containing ligands ligands for treatment of cancer | University Court | 2004-11-04 | — | — | US | disclosed |
| US-6750251-B2 | TO PRODUCE MEDICAMENT FOR THERAPY AND PROPHYLAXIS OF CANCER | THE UNIVERSITY COURT, THE UNIVERSITY OF EDINBURGH (UK) (GB) | 2004-06-15 | — | — | US | disclosed |
| US-20030023088-A1 | Half-sandwich ruthenium (II) compounds comprising nitrogen containing ligands for treatment of cancer | UNIVERSITY COURT, THE UNIVERSITY OF EDINBURGH (UK), THE (GB) | 2003-01-30 | — | — | US | disclosed |
| JP-S60190756-A | PRODUCTION OF 1,7-DI(4-HYDROXYPHENYLTHIO)-3,5-DIOXAHEPTANE | RICOH CO LTD | 1985-09-28 | — | — | JP | disclosed |
| EP-0022081-B1 | POLYMERISABLE COMPOSITIONS CONTAINING SULPHOXONIUM SALTS AND PROCESS FOR THE PRODUCTION OF HIGH MOLECULAR WEIGHT PRODUCTS FROM THESE COMPOSITIONS BY IRRADIATION | CIBA-GEIGY AG (CH) | 1983-02-09 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050239765-A1 | Half-sandwich ruthenium (II) compounds comprising nitrogen containing ligands for treatment of cancer | NR0B1, NR0B2, NCOR1 | RECQL 998/4885TSHR 53/4885MAOB 3919/4885 |
| US-20100291236-A1 | OSMIUM COMPOUNDS | OGFR, OGFRL1, AQP1 | RECQL 3811/4885TSHR 2144/4885MAOB 2157/4885 |
| US-20030023088-A1 | Half-sandwich ruthenium (II) compounds comprising nitrogen containing ligands for treatment of cancer | NR0B1, CBR1, NR0B2 | RECQL 429/4885TSHR 424/4885MAOB 1364/4885 |
| US-20040220166-A1 | Half-sandwich ruthenium (II) compounds comprising nitrogen containing ligands ligands for treatment of cancer | NR0B1, NR0B2, NR4A1 | RECQL 483/4885TSHR 195/4885MAOB 3136/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.